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Long Interspersed Elements

Known as: Sequences, LINE Repeat, Long Interspersed Element, Repeat Sequence, LINE 
Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is… Expand
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Chromosome Structures
Chromosomesaspects of radiation effectsphysiological aspects

Narrower (2)

Jockey ElementsLong Interspersed Nucleotide Element-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
A unique regulatory phase of DNA methylation in the early mammalian embryo
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively… Expand
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Highly Cited
2010
Highly Cited
2010
Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences.
Interspersed repetitive sequences (IRSs) are a major contributor to genome size and may contribute to cellular functions. IRSs… Expand
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Highly Cited
2010
Highly Cited
2010
Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects.
BACKGROUND Impaired one-carbon metabolism is thought to be associated with the risk of neural tube defects (NTDs); however, the… Expand
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Highly Cited
2009
Highly Cited
2009
L1 retrotransposition in human neural progenitor cells
Long interspersed element 1 (LINE-1 or L1) retrotransposons have markedly affected the human genome. L1s must retrotranspose in… Expand
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Highly Cited
2006
Highly Cited
2006
Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.
Long interspersed element (LINE) 1 retrotransposons are major genomic parasites that represent approximately 17% of the human… Expand
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Highly Cited
2005
Highly Cited
2005
The profile of repeat‐associated histone lysine methylation states in the mouse epigenome
Histone lysine methylation has been shown to index silenced chromatin regions at, for example, pericentric heterochromatin or of… Expand
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Highly Cited
2004
Highly Cited
2004
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements.
We report a method for studying global DNA methylation based on using bisulfite treatment of DNA and simultaneous PCR of multiple… Expand
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Highly Cited
2000
Highly Cited
2000
Human LINE retrotransposons generate processed pseudogenes
Long interspersed elements (LINEs) are endogenous mobile genetic elements that have dispersed and accumulated in the genomes of… Expand
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Highly Cited
2000
Highly Cited
2000
Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis.
X inactivation is a chromosome-specific form of genetic regulation in which thousands of genes on one homologue become silenced… Expand
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Highly Cited
1999
Highly Cited
1999
Phylogenetic relationships among cetartiodactyls based on insertions of short and long interpersed elements: hippopotamuses are the closest extant relatives of whales.
Insertion analysis of short and long interspersed elements is a powerful method for phylogenetic inference. In a previous study… Expand
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