Long Interspersed Elements

Known as: Sequences, LINE Repeat, Long Interspersed Element, Repeat Sequence, LINE 
Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is… (More)
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Chromosome Structures
Chromosomesaspects of radiation effectsphysiological aspects

Narrower (2)

Jockey ElementsLong Interspersed Nucleotide Element-1

Papers overview

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Highly Cited
2012
Highly Cited
2012
A unique regulatory phase of DNA methylation in the early mammalian embryo
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively… (More)
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Highly Cited
2010
Highly Cited
2010
Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences.
Interspersed repetitive sequences (IRSs) are a major contributor to genome size and may contribute to cellular functions. IRSs… (More)
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Highly Cited
2010
Highly Cited
2010
Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects.
BACKGROUND Impaired one-carbon metabolism is thought to be associated with the risk of neural tube defects (NTDs); however, the… (More)
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Highly Cited
2006
Highly Cited
2006
Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.
Long interspersed element (LINE) 1 retrotransposons are major genomic parasites that represent approximately 17% of the human… (More)
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Review
2006
Review
2006
Retrotransposable elements and human disease.
Nearly 50% of the human genome is composed of fossils from the remains of past transposable element duplication. Mobilization… (More)
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Highly Cited
2004
Highly Cited
2004
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements.
We report a method for studying global DNA methylation based on using bisulfite treatment of DNA and simultaneous PCR of multiple… (More)
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Highly Cited
2000
Highly Cited
2000
Human LINE retrotransposons generate processed pseudogenes
Long interspersed elements (LINEs) are endogenous mobile genetic elements that have dispersed and accumulated in the genomes of… (More)
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Highly Cited
1999
Highly Cited
1999
Phylogenetic relationships among cetartiodactyls based on insertions of short and long interpersed elements: hippopotamuses are the closest extant relatives of whales.
Insertion analysis of short and long interspersed elements is a powerful method for phylogenetic inference. In a previous study… (More)
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Highly Cited
1999
Highly Cited
1999
CORE-SINEs: eukaryotic short interspersed retroposing elements with common sequence motifs.
A 65-bp "core" sequence is dispersed in hundreds of thousands copies in the human genome. This sequence was found to constitute… (More)
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Highly Cited
1990
Highly Cited
1990
Differential distribution of long and short interspersed element sequences in the mouse genome: chromosome karyotyping by fluorescence in situ hybridization.
Fluorescence in situ hybridization has been used to demonstrate the differential distribution of interspersed repetitive elements… (More)
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