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Long Interspersed Elements
Known as:
Sequences, LINE Repeat
, Long Interspersed Element
, Repeat Sequence, LINE
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Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is…
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National Institutes of Health
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Related topics
Related topics
6 relations
Broader (1)
Chromosome Structures
Chromosomes
aspects of radiation effects
physiological aspects
Narrower (2)
Jockey Elements
Long Interspersed Nucleotide Element-1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
A unique regulatory phase of DNA methylation in the early mammalian embryo
Zachary D. Smith
,
Michelle M. Chan
,
+4 authors
A. Meissner
Nature
2012
Corpus ID: 1527411
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively…
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Highly Cited
2010
Highly Cited
2010
Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences.
P. Jintaridth
,
A. Mutirangura
Physiological Genomics
2010
Corpus ID: 7825530
Interspersed repetitive sequences (IRSs) are a major contributor to genome size and may contribute to cellular functions. IRSs…
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Highly Cited
2009
Highly Cited
2009
L1 retrotransposition in human neural progenitor cells
N. Coufal
,
J. García-Pérez
,
+7 authors
F. Gage
Nature
2009
Corpus ID: 4354992
Long interspersed element 1 (LINE-1 or L1) retrotransposons have markedly affected the human genome. L1s must retrotranspose in…
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Review
2007
Review
2007
Survey Sequencing and Comparative Analysis of the Elephant Shark (Callorhinchus milii) Genome
B. Venkatesh
,
E. Kirkness
,
+9 authors
S. Brenner
PLoS Biology
2007
Corpus ID: 15160087
Owing to their phylogenetic position, cartilaginous fishes (sharks, rays, skates, and chimaeras) provide a critical reference for…
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Highly Cited
2006
Highly Cited
2006
Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.
H. Bogerd
,
H. Wiegand
,
+4 authors
B. Cullen
Proceedings of the National Academy of Sciences…
2006
Corpus ID: 26337446
Long interspersed element (LINE) 1 retrotransposons are major genomic parasites that represent approximately 17% of the human…
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Highly Cited
2005
Highly Cited
2005
The profile of repeat‐associated histone lysine methylation states in the mouse epigenome
J. Martens
,
R. O’Sullivan
,
+4 authors
T. Jenuwein
EMBO Journal
2005
Corpus ID: 7842830
Histone lysine methylation has been shown to index silenced chromatin regions at, for example, pericentric heterochromatin or of…
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Highly Cited
2004
Highly Cited
2004
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements.
A. Yang
,
M. Estécio
,
Ketan Doshi
,
Y. Kondo
,
E. Tajara
,
J. Issa
Nucleic Acids Research
2004
Corpus ID: 19742949
We report a method for studying global DNA methylation based on using bisulfite treatment of DNA and simultaneous PCR of multiple…
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Highly Cited
2000
Highly Cited
2000
Human LINE retrotransposons generate processed pseudogenes
Cécile Esnault
,
J. Maestre
,
T. Heidmann
Nature Genetics
2000
Corpus ID: 6587285
Long interspersed elements (LINEs) are endogenous mobile genetic elements that have dispersed and accumulated in the genomes of…
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Highly Cited
2000
Highly Cited
2000
Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis.
J. Bailey
,
L. Carrel
,
A. Chakravarti
,
E. Eichler
Proceedings of the National Academy of Sciences…
2000
Corpus ID: 8171837
X inactivation is a chromosome-specific form of genetic regulation in which thousands of genes on one homologue become silenced…
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Highly Cited
1999
Highly Cited
1999
Phylogenetic relationships among cetartiodactyls based on insertions of short and long interpersed elements: hippopotamuses are the closest extant relatives of whales.
M. Nikaido
,
A. Rooney
,
N. Okada
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 725704
Insertion analysis of short and long interspersed elements is a powerful method for phylogenetic inference. In a previous study…
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