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Lobeline

Known as: Inflatine, 2-(6-(Beta-Hydroxyphenethyl)-1-Methyl-2-Piperidyl)acetophenone, Lobeline [Chemical/Ingredient] 
An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background Drug repositioning offers the possibility of faster development times and reduced risks in drug discovery. With the… Expand
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Highly Cited
2007
Highly Cited
2007
Lobeline has been prepared in enantiopure form via desymmetrization of lobelanidine with use of BTM, a nonenzymatic… Expand
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Highly Cited
2005
Highly Cited
2005
Upon ligand binding at the subunit interfaces, the extracellular domain of the nicotinic acetylcholine receptor undergoes… Expand
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Highly Cited
2004
Highly Cited
2004
Lobeline attenuates the behavioral effects of psychostimulants in rodents and inhibits the function of nicotinic receptors… Expand
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Review
2002
Review
2002
Lobeline, an alkaloidal constituent of Lobelia inflata LINN., has a long history of therapeutic usage ranging from emetic and… Expand
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Highly Cited
2001
Highly Cited
2001
Lobeline interacts with the dopamine transporter and vesicular monoamine transporter, presynaptic proteins involved in dopamine… Expand
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Review
2001
Review
2001
Neuronal nicotinic acetylcholine receptors are distributed extensively throughout the central and peripheral nervous systems… Expand
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Highly Cited
2001
Highly Cited
2001
alpha-Lobeline inhibits d-amphetamine-evoked dopamine release from striatal slices in vitro, appearing to reduce the cytosolic… Expand
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Review
2000
Review
2000
Few people now dispute that smoking is damaging human health on a global scale.1 However, many governments have avoided taking… Expand
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Highly Cited
1997
Highly Cited
1997
In this study we investigated the pharmacology of lobeline, a high affinity nicotinic ligand with a unique pharmacological… Expand
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