Skip to search formSkip to main contentSkip to account menu

Lobeline

Known as: Inflatine, 2-(6-(Beta-Hydroxyphenethyl)-1-Methyl-2-Piperidyl)acetophenone, Lobeline [Chemical/Ingredient] 
An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of… 
National Institutes of Health

Related topics

Related topics

17 relations

Narrower (6)

CRM I-13-1CRM I-32-1Lobeline SulfateSmokeless

Broader (3)

Ganglionic StimulantsNicotinic AgonistsRespiratory System Agents
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Morphine dependence and withdrawal induced changes in cholinergic signaling
2005
2005
Effects on serotonin of (−)nicotine and dimethylphenylpiperazinium in the dorsal raphe and nucleus accumbens of freely behaving rats
Highly Cited
2004
Highly Cited
2004
Modulation of autonomous contractile activity in the isolated whole bladder of the guinea pig
The over active bladder and bladder outlet obstruction represent clinically significant problems. The first two papers of this… 
2001
2001
The effect of plant growth regulators on biomass formation and lobeline production of Lobelia inflata L. hairy root cultures
We have studied the biomass and alkaloid production of geneticallytransformed hairy root cultures of Lobelia inflata L. Thehairy… 
Highly Cited
1999
Highly Cited
1999
Lobeline: structure-affinity investigation of nicotinic acetylcholinergic receptor binding.
(-)Lobeline (1) and (-)nicotine (2) bind at neuronal nicotinic cholinergic (nACh) receptors with high affinity (K(i) = 4 and 2 nM… 
Highly Cited
1997
Highly Cited
1997
Prenatal nicotine sex-dependently alters agonist-induced locomotion and stereotypy.
1991
1991
SKF 525-A and cytochrome P-450 ligands inhibit with high affinity the binding of [3H]dextromethorphan and sigma ligands to guinea pig brain.
Highly Cited
1984
Highly Cited
1984
Nature of nicotine binding to rat brain P2 fraction
1967
1967
Effects of pharmacological agents on the physiological responses of hair discs.
Review
1959
Review
1959
The primary hypoventilation syndrome.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)