Lobeline

Known as: Inflatine, 2-(6-(Beta-Hydroxyphenethyl)-1-Methyl-2-Piperidyl)acetophenone, Lobeline [Chemical/Ingredient] 
An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
05101519472017

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Drug repositioning offers the possibility of faster development times and reduced risks in drug discovery. With the… (More)
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Highly Cited
2009
Highly Cited
2009
Contact chemosensation is required for several behaviors that promote insect survival. These include evasive behaviors such as… (More)
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Highly Cited
2005
Highly Cited
2005
Upon ligand binding at the subunit interfaces, the extracellular domain of the nicotinic acetylcholine receptor undergoes… (More)
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2002
2002
Abstract Rationale. Previous results demonstrated that pretreatment with lobeline attenuates d-methamphetamine self… (More)
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2001
2001
alpha-Lobeline inhibits d-amphetamine-evoked dopamine release from striatal slices in vitro, appearing to reduce the cytosolic… (More)
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2001
2001
Lobeline interacts with the dopamine transporter and vesicular monoamine transporter, presynaptic proteins involved in dopamine… (More)
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1997
1997
In this study we investigated the pharmacology of lobeline, a high affinity nicotinic ligand with a unique pharmacological… (More)
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1997
1997
Lobeline is currently being developed as a substitution therapy for tobacco smoking cessation. Activation of CNS dopamine (DA… (More)
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1994
1994
In normal subjects, if an acoustic startle stimulus is immediately preceded by a small brief change in background noise intensity… (More)
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1990
1990
Previous work has suggested that cytisine and lobeline are of low potency in producing nicotine-like behavioural effects, despite… (More)
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