Lithocholic Acid

Known as: Acid, Lithocholic, Lithocholic Acid [Chemical/Ingredient], Cholan-24-oic acid, 3-hydroxy-, (3alpha,5beta)- 
A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1940-2017
0204019402016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
The physiological ligand for the vitamin D receptor (VDR) is 1,25-dihydroxyvitamin D(3). Lithocholic acid (LCA), a bile acid… (More)
Is this relevant?
2006
2006
We determined the mechanisms of hepatobiliary injury in the lithocholic acid (LCA)-fed mouse, an increasingly used model of… (More)
Is this relevant?
2003
2003
Supplement of 1% lithocholic acid (LCA) in the diet for 5-9 days resulted in elevated levels of the marker for liver damage… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The vitamin D receptor (VDR) mediates the effects of the calcemic hormone 1alpha,25-dihydroxyvitamin D3 [1,25(OH)2D3]. We show… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16alpha-carbonitrile (PCN… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Hepatic hydroxylation is an essential step in the metabolism and excretion of bile acids and is necessary to avoid pathologic… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Bile acids regulate the transcription of genes that control cholesterol homeostasis through molecular mechanisms that are poorly… (More)
Is this relevant?
1999
1999
The aim of the present study was to identify the enzymes in human liver catalyzing hydroxylations of bile acids. Fourteen… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
A reversed phase high pressure liquid chromatography (HPLC) system capable of simultaneously separating four lithocholyl species… (More)
Is this relevant?
Highly Cited
1977
Highly Cited
1977
Because of potential significance of bile acids and cholesterol metabolites in the pathogenesis of colon cancer, fecal neutral… (More)
Is this relevant?