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Lithocholic Acid

Known as: Acid, Lithocholic, Lithocholic Acid [Chemical/Ingredient], Cholan-24-oic acid, 3-hydroxy-, (3alpha,5beta)- 
A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The hormonal metabolite of vitamin D, 1α,25-dihydroxyvitamin D3 (1,25D), initiates biological responses via binding to the… Expand
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Highly Cited
2009
Highly Cited
2009
We demonstrate the aptitude of supramolecular hydrogel formation using simple bile acid such as lithocholic acid in aqueous… Expand
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Highly Cited
2006
Highly Cited
2006
We determined the mechanisms of hepatobiliary injury in the lithocholic acid (LCA)-fed mouse, an increasingly used model of… Expand
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Highly Cited
2005
Highly Cited
2005
Cytochrome P450 (P450) enzymes play important roles in the metabolism of endogenous and xenobiotic substrates in humans. CYP2C8… Expand
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Review
2004
Review
2004
Lithocholic acid, a monohydroxy, secondary bile acid, is formed by bacterial 7‐dehydroxylation of the primary bile acid… Expand
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Highly Cited
2002
Highly Cited
2002
The vitamin D receptor (VDR) mediates the effects of the calcemic hormone 1α,25-dihydroxyvitamin D3[1,25(OH)2D3]. We show that… Expand
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Highly Cited
2001
Highly Cited
2001
The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16α-carbonitrile (PCN), which… Expand
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Highly Cited
2001
Highly Cited
2001
Hepatic hydroxylation is an essential step in the metabolism and excretion of bile acids and is necessary to avoid pathologic… Expand
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Highly Cited
1999
Highly Cited
1999
Bile acids regulate the transcription of genes that control cholesterol homeostasis through molecular mechanisms that are poorly… Expand
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Review
1993
Review
1993
The development and life-time of multicellular eukaryotic organisms represents a complex interplay of numerous proliferation and… Expand
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