Lipofuscin

Known as: Lipofuscin [Chemical/Ingredient], Lipofuscins, Senility pigment 
A naturally occurring lipid pigment with histochemical characteristics similar to ceroid. It accumulates in various normal tissues and apparently… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Recent studies have implicated local inflammation and activation of complement amongst the processes involved in the pathogenesis… (More)
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Review
2005
Review
2005
Lipofuscin is membrane-bound cellular waste that can be neither degraded nor ejected from the cell but can only be diluted… (More)
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Review
2002
Review
2002
The accumulation of lipofuscin within postmitotic cells is a recognized hallmark of aging occurring with a rate inversely related… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To characterize the age-related accumulation of lipofuscin in a population of normal subjects, resolve differences in… (More)
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Highly Cited
2000
Highly Cited
2000
We have studied the effects of hyperoxia and of cell loading with artificial lipofuscin or ceroid pigment on the postmitotic… (More)
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Highly Cited
1999
Highly Cited
1999
The fluorescent pigment lipofuscin accumulates with age in the cytoplasm of cells of the CNS. Because of its broad excitation and… (More)
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Highly Cited
1995
Highly Cited
1995
PURPOSE To characterize the intrinsic fluorescence (autofluorescence) of the human ocular fundus with regard to its excitation… (More)
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Highly Cited
1993
Highly Cited
1993
Despite the association between high concentrations of the age pigment lipofuscin and various age-related pathologies, there is… (More)
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Highly Cited
1980
Highly Cited
1980
Analysis of the fluorescent spectra of chloroform-methanol extracts of human retinal pigment epithelium confirmed the presence of… (More)
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Highly Cited
1978
Highly Cited
1978
The life history of melanin and lipofuscin granules of human retinal pigment epithelium (RPE) was studied in 30 human eyes… (More)
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