Lidoflazine

Known as: 1-Piperazineacetamide, 4-(4,4-bis(4-fluorophenyl)butyl)-N-(2,6-dimethylphenyl)-, Lidoflazine [Chemical/Ingredient] 
Coronary vasodilator with some antiarrhythmic action.
National Institutes of Health

Related topics

Related topics

10 relations

Broader (2)

Calcium Channel BlockersVasodilator Agents

Narrower (1)

Clinium
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

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1997
1997
Asphyxiation versus ventricular fibrillation cardiac arrest in dogs. Differences in cerebral resuscitation effects--a preliminary study.
UNLABELLED We explored the hypothesis that brain damage after cardiac arrest caused by ventricular fibrillation (VF) needs… (More)
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Highly Cited
1991
Highly Cited
1991
Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism.
The level of purines in the striatum of awake, freely moving rats was studied using microdialysis. The calculated extracellular… (More)
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1988
1988
Comparative protective effects of nicardipine, flunarizine, lidoflazine and nimodipine against ischaemic injury in the hippocampus of the Mongolian gerbil.
1. Morphological changes characterizing delayed neuronal death (DND) of selectively vulnerable CA1 pyramidal cells in the… (More)
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Highly Cited
1987
Highly Cited
1987
Cerebral ischemia and reperfusion: prevention of brain mitochondrial injury by lidoflazine.
Mitochondrial degradation is implicated in the irreversible cell damage that can occur during cerebral ischemia and reperfusion… (More)
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1985
1985
The effects of lidoflazine and flunarizine on cerebral reactive hyperemia.
Cerebral blood flow in the rat was monitored by a venous outflow technique with an extracorporeal circulation, which allows for… (More)
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1984
1984
Amelioration of brain damage by lidoflazine after prolonged ventricular fibrillation cardiac arrest in dogs.
Calcium entry blockers can ameliorate postischemic cerebral hypoperfusion, protect the myocardium against ischemia, and may… (More)
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1984
1984
Effect of lidoflazine on cerebral blood flow following twelve minutes total cerebral ischemia.
Lidoflazine, a calcium channel blocker, was administered to dogs following twelve minutes of cerebral ischemia, induced by aortic… (More)
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1983
1983
Early amelioration of neurologic deficit by lidoflazine after fifteen minutes of cardiopulmonary arrest in dogs.
A prospective, controlled, blind study was done to test the effect of a calcium entry blocker on the neurologic integrity of dogs… (More)
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1981
1981
Cardioprotective effects of lidoflazine during 1-hour normothermic global ischemia.
The cardioprotective effects of lidoflazine, a drug with calcium homeostatic properties, were investigated in dogs subjected to 1… (More)
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1965
1965
Stimulation of the coronary collateral circulation by lidoflazine (R 7904)
Lidoflazine, a new and very longacting coronary vasodilator was given to 18 dogs with a chronically developing stenosis and… (More)
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