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Licensing Factor

S-phase onset is controlled, so that it occurs only once every cell cycle. DNA is licensed for replication after mitosis in G(1), and passage through… Expand
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
HBO1, an H4-specific histone acetylase, is a coactivator of the DNA replication licensing factor Cdt1. HBO1 acetylase activity is… Expand
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Highly Cited
2008
Highly Cited
2008
The faithful replication of genomic DNA is crucial for maintaining genome stability. In eukaryotes, DNA rereplication is… Expand
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Highly Cited
2005
Highly Cited
2005
Cyclin-dependent kinases (CDKs) restrict DNA replication origin firing to once per cell cycle by preventing the assembly of… Expand
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Highly Cited
2004
Highly Cited
2004
To act as guides in the RNA interference (RNAi) pathway, small interfering RNAs (siRNAs) must be unwound into their component… Expand
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Highly Cited
2004
Highly Cited
2004
Licensing of replication origins is carefully regulated in a cell cycle to maintain genome integrity. Using an in vivo… Expand
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Highly Cited
2003
Highly Cited
2003
DNA replication initiation is tightly controlled so that each origin only fires once per cell cycle. Cell cycle-dependent Cdt1… Expand
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Highly Cited
2001
Highly Cited
2001
S-phase onset is controlled, so that it occurs only once every cell cycle. DNA is licensed for replication after mitosis in G1… Expand
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Highly Cited
1995
Highly Cited
1995
REPLICATION licensing factor (RLF) ensures that eukaryotic chromosomal DNA is replicated exactly once in each cell cycle1–4. On… Expand
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Highly Cited
1995
Highly Cited
1995
Replication licensing factor is thought to be involved in the strict control of the initiation of DNA replication in eukaryotes… Expand
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Highly Cited
1994
Highly Cited
1994
The integration of chromosomal DNA replication into the eukaryotic cell cycle might involve temporal regulation of interactions… Expand
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