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Leukotriene Production

Leukotriene Production consists of synthesis of a family of oxidative derivatives of arachidonic acid (5-lipoxygenase pathway) (leukotrienes) having… 
National Institutes of Health

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Related topics

7 relations
ALOX12 geneALOX12 wt AlleleALOX12B geneALOX12B wt Allele

Papers overview

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Highly Cited
2009
Highly Cited
2009
Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia.
2008
2008
Honeybee venom secretory phospholipase A2 induces leukotriene production but not histamine release from human basophils
The role of basophils in an anaphylactic response is well recognized but is usually masked by mast cells, which contain similar… 
2004
2004
Cerebral ischemia in 5-lipoxygenase knockout mice
Highly Cited
2001
Highly Cited
2001
Mechanism of Human Group V Phospholipase A2(PLA2)-induced Leukotriene Biosynthesis in Human Neutrophils
Human group V phospholipase A2(hVPLA2) has been shown to have high activity to elicit leukotriene production in human neutrophils… 
2000
2000
Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition.
Review
1999
Review
1999
Asthma therapy with agents preventing leukotriene synthesis or action.
Elucidation of the biochemistry of leukotriene production and the pharmacology of its actions has led to the development of a… 
1998
1998
The role of platelet activating factor and other lipid mediators in inflammatory angiogenesis.
Highly Cited
1989
Highly Cited
1989
Effects of sulfasalazine and a sulfasalazine analogue on the formation of lipoxygenase and cyclooxygenase products.
Highly Cited
1988
Highly Cited
1988
Potentiation of leukotriene production following sequestration of neutrophils in isolated lungs: indirect evidence for intercellular leukotriene A4 transfer.
Granulocyte (polymorphonuclear leukocyte, PMN) sequestration in the microvascular bed with release of different mediators has… 
Highly Cited
1982
Highly Cited
1982
New role for 15-hydroxyeicosatetraenoic acid. Activator of leukotriene biosynthesis in PT-18 mast/basophil cells.
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