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Leukocyte-Adhesion Deficiency Syndrome

Known as: Syndrome, Leukocyte-Adhesion Deficiency, Deficiency Syndrome, Leukocyte-Adhesion, Deficiency Syndrome, Leukocyte Adhesion 
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18… 
National Institutes of Health

Related topics

Related topics

10 relations
CD18 AntigensIn BloodMicrobiologicalReceptors, Leukocyte-Adhesion

Narrower (2)

Leukocyte Adhesion Deficiency, Type IIILeukocyte adhesion deficiency type 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Adaptive Immune Response to Model Antigens Is Impaired in Murine Leukocyte-Adhesion Deficiency-1 Revealing Elevated Activation Thresholds In Vivo
Absence of β 2 integrins (CD11/CD18) leads to leukocyte-adhesion deficiency-1 (LAD1), a rare primary immunodeficiency syndrome… 
2010
2010
PCR based identification of bovine leukocyte adhesion deficiency syndrome (BLAD) carriers in Karan Fries bulls.
Bovine leukocyte adhesion deficiency syndrome (BLAD) is a lethal autosomal and recessive inherited disease in Holstein Frisian… 
Review
2007
Review
2007
Mutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3.
The leukocyte beta2 integrins are heterodimeric adhesion receptors required for a functional immune system. Many leukocyte… 
1999
1999
Continuous heparinization and circulating adhesion molecules in the critically ill.
Endothelial activation and damage are common endpoints of a complex process that may result in multiple organ dysfunction… 
1997
1997
Alteration in leukocyte adhesion molecule expression following minor, moderate and major trauma.
An understanding of the mechanisms of post-injury leukocyte trafficking is essential to the development of future therapeutic… 
Highly Cited
1995
Highly Cited
1995
Levels of soluble adhesion molecules and cytokines in patients with septic multiple organ failure.
Multiple organ failure (MOF) is a common complication of sepsis or septic shock. In this condition, it is believed that activated… 
1994
1994
Heterogeneous activation thresholds to cytokines in genetically distinct endothelial cells: evidence for diverse transcriptional responses.
It is well accepted that the induction of endothelial cell (EC) adhesion molecules is a critical component in acute inflammatory… 
1993
1993
Fetal Neutrophils and Eosinophils Express Normal Levels of L-Selectin
ABSTRACT: L-selectin is a leukocyte adhesion molecule important in the initial stages of the interaction of neutrophils with… 
1992
1992
Distribution of lymphocytes and cell adhesion molecules in iris biopsy specimens from patients with uveitis.
To investigate the mechanisms responsible for lymphocyte accumulation in the eye in uveitis, we examined iris biopsy specimens… 
1991
1991
Adhesion molecules in the pathogenesis of asthma.
Using a primate antigen inhalation model the mechanisms involved in the induction of airway hyperresponsiveness were studied… 
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