Leukocyte-Adhesion Deficiency Syndrome

Known as: Syndrome, Leukocyte-Adhesion Deficiency, Deficiency Syndrome, Leukocyte-Adhesion, Deficiency Syndrome, Leukocyte Adhesion 
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Integrin activation is essential for the function of all blood cells, including platelets and leukocytes. The blood cell–specific… (More)
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2003
2003
Recently, we reported a rare leukocyte adhesion deficiency (LAD) associated with severe defects in integrin activation by… (More)
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Highly Cited
1999
Highly Cited
1999
Whereas ligation of the DNAM-1 adhesion molecule triggers cytotoxicity mediated by normal NK and T cells, this function was… (More)
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1999
1999
INTRODUCTION Leukocyte adhesion deficiency syndrome (LAD) is an altered phagocytic disorder characterised by the deficiency of… (More)
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1995
1995
We have previously reported a newly discovered congenital disorder of neutrophil adhesion, leukocyte adhesion deficiency syndrome… (More)
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Highly Cited
1993
Highly Cited
1993
OBJECTIVE To define the immunohistologic features of the synovial membrane (SM) of patients with psoriatic arthritis (PA) and to… (More)
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Highly Cited
1992
Highly Cited
1992
The present studies were performed to explore potentially selective mechanisms of leukocyte adhesion in an attempt to understand… (More)
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Highly Cited
1992
Highly Cited
1992
Previous studies have shown enhanced neutrophil adhesion to endothelial cells exposed to anoxia and then reoxygenated (A/R). To… (More)
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Highly Cited
1990
Highly Cited
1990
We have used three-color flow cytometry to investigate the pattern of expression of the CD11/CD18, CD44, and leukocyte adhesion… (More)
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Highly Cited
1989
Highly Cited
1989
Focal adhesion of leukocytes to the blood vessel lining is a key step in inflammation and certain vascular disease processes… (More)
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