Leukocyte-Adhesion Deficiency Syndrome
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Integrin activation is essential for the function of all blood cells, including platelets and leukocytes. The blood cell–specific… Expand Recently, we reported a rare leukocyte adhesion deficiency (LAD) associated with severe defects in integrin activation by… Expand We have previously reported a newly discovered congenital disorder of neutrophil adhesion, leukocyte adhesion deficiency syndrome… Expand OBJECTIVE
To define the immunohistologic features of the synovial membrane (SM) of patients with psoriatic arthritis (PA) and to… Expand The present studies were performed to explore potentially selective mechanisms of leukocyte adhesion in an attempt to understand… Expand Previous studies have shown enhanced neutrophil adhesion to endothelial cells exposed to anoxia and then reoxygenated (A/R). To… Expand Leukocyte adherence to endothelium is in part mediated by the transient expression of endothelial-leukocyte adhesion molecule 1… Expand A CENTRAL feature of host defence is the ability of leukocytes to enter tissues in response to immune or inflammatory stimuli… Expand There is increasing evidence that cytokines such as granulocyte-macrophage (GM)-CSF can profoundly affect the adhesion… Expand Focal adhesion of leukocytes to the blood vessel lining is a key step in inflammation and certain vascular disease processes… Expand