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Leucine

Known as: (S)-(+)-Leucine, Leucine [Chemical/Ingredient], Leucine, L-Isomer 
One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (33)

(S)-gamma-fluoroleucine ethyl ester4-amino-6-methylhept-2-enoic acidAF40431BB 882

Broader (2)

Amino Acidsnonpolar amino acids
In BloodIsoleucine / Leucine / ValineLeucine:SCnc:Pt:CSF:QnPERIKABIVEN INJ

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity.
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) cause late-onset Parkinson's disease (PD) with a clinical appearance… 
Highly Cited
2004
Highly Cited
2004
Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology
Highly Cited
2002
Highly Cited
2002
Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics*
Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric… 
Highly Cited
2001
Highly Cited
2001
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… 
Highly Cited
1996
Highly Cited
1996
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
Transgenic mice overexpressing the 695-amino acid isoform of human Alzheimer β-amyloid (Aβ) precursor protein containing a Lys670… 
Highly Cited
1994
Highly Cited
1994
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
RECENT studies suggest that pro teases of the inter leukin 1-β-con-verting enzyme (ICE)/ced-3 family are involved in initiating… 
Highly Cited
1990
Highly Cited
1990
Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy.
Highly Cited
1986
Highly Cited
1986
A new method for predicting signal sequence cleavage sites.
A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the… 
Highly Cited
1975
Highly Cited
1975
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Enkephalin, a natural ligand for opiate receptors is composed of the pentapeptides H–Tyr–Gly–Gly–Phe–Met–OH and H–Tyr–Gly–Gly–Phe… 
Highly Cited
1954
Highly Cited
1954
A modified ninhydrin reagent for the photometric determination of amino acids and related compounds.
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