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BB 882

Known as: BB-882 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Leucine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Effects of lexipafant (BB-882), a platelet activating factor receptor antagonist, on liver damage due to bile duct ligation in rats.
BACKGROUND AND STUDY AIMS Extrahepatic cholestasis is one of the main factors causing liver fibrosis. In this study, we aimed to… 
2003
2003
Influence of the Platelet-Activating Factor Receptor Antagonist BB-882 on Intra-Abdominal Adhesion Formation in Rats
Postoperative intra-abdominal adhesion formation is a major clinical problem. We aimed to examine the preventive effect of… 
Highly Cited
1999
Highly Cited
1999
Inhibition of platelet‐activating factor, intercellular adhesion molecule 1 and platelet endothelial cell adhesion molecule 1 reduces experimental pancreatitis‐associated gut endothelial barrier…
Endothelial barrier dysfunction is a critical link in the development of tissue injury and organ dysfunction, via upregulation… 
1998
1998
Effect of a Platelet‐Activating Factor Antagonist on Pancreatitis‐Associated Gut Barrier Dysfunction in Rats
Platelet-activating factor (PAF) may play a critical and primary role in the pathogenesis of acute pancreatitis and pancreatitis… 
1996
1996
Lung injury in the microembolic model of acute pancreatitis and amelioration by lexipafant (BB-882), a platelet-activating factor antagonist.
Acute pancreatitis is associated with the development of pulmonary dysfunction in a number of patients. The aim of this study was… 
1996
1996
Lung Injury in the Microembolic Model of Acute Pancreatitis and Amelioration by Lexipafant (BB‐882), a Platelet‐Activating Factor Antagonist
&NA; Acute pancreatitis is associated with the development of pulmonary dysfunction in a number of patients. The aim of this… 
Review
1996
Review
1996
Lexipafant (BB-882), a potent PAF antagonist in acute pancreatitis.
Acute pancreatitis remains a poorly understood and hence unsatisfactorily treated condition1. In general this is a mild self… 
1996
1996
BB-882 is a potent antagonist of the haemodynamic changes induced by platelet-activating factor in pigs.
The effects of bolus doses (0.2-2 micrograms) of platelet-activating factor (PAF) on systemic and pulmonary arterial pressures… 
1996
1996
Role of platelet-activating factor antagonism in posthemorrhage septic shock in pigs.
OBJECTIVES To study the role of platelet-activating factor (PAF) antagonism in posthemorrhage septic shock in pigs. DESIGN… 
1996
1996
Platelet activating factor antagonism improves cardiovascular function in non-hypotensive sepsis in pigs.
OBJECTIVE To study the effects of platelet activating factor (PAF) antagonism on cardiovascular function in Escherichia coli… 
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