Skip to search formSkip to main contentSkip to account menu

Leucine Zippers

Known as: Leucine Zipper, Zipper, Leucine, Zippers, Leucine 
DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped… 
National Institutes of Health

Related topics

Related topics

26 relations
ATF2 protein, humanATF4 protein, humanAndrogen-Induced Prostate Proliferative Shutoff Associated ProteinBasic Helix-Loop-Helix Leucine Zipper Transcription Factors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice
ACTIVATING transcription factor-2 (ATF-2) is a basic region leucine zipper protein whose DNA target sequence is the widely… 
Highly Cited
1995
Highly Cited
1995
Probing the folding mechanism of a leucine zipper peptide by stopped-flow circular dichroism spectroscopy.
Leucine zipper peptides provide simple model systems for studying both the intramolecular and intermolecular interactions that… 
Highly Cited
1995
Highly Cited
1995
A gene that is related to SRY and is expressed in the testes encodes a leucine zipper-containing protein
SRY-related cDNA encoding a protein with a high-mobility-group (HMG) box and a leucine zipper motif, which was designated SOX-LZ… 
Highly Cited
1995
Highly Cited
1995
Protein destabilization by electrostatic repulsions in the two‐stranded α‐helical coiled‐coil/leucine zipper
The destabilizing effect of electrostatic repulsions on protein stability has been studied by using synthetic two‐stranded… 
Highly Cited
1993
Highly Cited
1993
Cloning and expression of a mammalian Na+/amino acid cotransporter with sequence similarity to Na+/glucose cotransporters.
Highly Cited
1991
Highly Cited
1991
The BZLF1 protein of EBV has a coiled coil dimerisation domain without a heptad leucine repeat but with homology to the C/EBP leucine zipper.
The EBV transactivator protein BZLF1 can bind many sites in the EBV genome, most of which have homology to a consensus AP-1 site… 
Highly Cited
1990
Highly Cited
1990
Secondary structure of a leucine zipper determined by nuclear magnetic resonance spectroscopy.
Previous work has shown that a synthetic peptide corresponding to the leucine zipper region of the yeast transcriptional… 
Highly Cited
1989
Highly Cited
1989
Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein
c-Myc plays a part in the regulation of important cellular processes such as growth, differentiation and neoplastic… 
Highly Cited
1989
Highly Cited
1989
A protein that binds to a cis-acting element of wheat histone genes has a leucine zipper motif.
The structure and function of transcription factors of higher plants was studied by isolating cDNA clones encoding a wheat… 
Review
1989
Review
1989
The oncogene jun and nuclear signalling.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)