Skip to search formSkip to main contentSkip to account menu

Lethal Dose 50

Known as: Dose 50, Lethal, Lethal Dose - 50%, LC-50 
The dose of a chemical or biologic preparation (e.g., a bacterial exotoxin or a suspension of bacteria) that is likely to cause death in 50% of the… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

drug potency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Application of the biotic ligand model to predicting zinc toxicity to rainbow trout, fathead minnow, and Daphnia magna.
Highly Cited
1999
Highly Cited
1999
Molecular Medicine © 1999 The Picower Institute Press Infectivity of Scrapie Prions Bound to a Stainless
  • 1999
  • Corpus ID: 14726446
Highly Cited
1999
Highly Cited
1999
Simultaneous activity of MRP1 and Pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia.
In adult acute myeloid leukemia (AML), the weight of the contribution of the combined activity of Pgp and MRP1 to drug resistance… 
Highly Cited
1996
Highly Cited
1996
Estradiol protects against β-amyloid (25–35)-induced toxicity in SK-N-SH human neuroblastoma cells
Highly Cited
1995
Highly Cited
1995
Thermal and behavioral effects of lipopolysaccharide and influenza in interleukin-1 beta-deficient mice.
This study characterized body temperature (Tb), locomotor activity (Act), and feeding behavior under normal conditions and… 
Highly Cited
1979
Highly Cited
1979
The protection of primates against soman poisoning by pretreatment with pyridostigmine
The effectiveness of pyridostigmine pretreatment against soman poisoning has been determined in rhesus monkeys and marmosets… 
Highly Cited
1979
Highly Cited
1979
Natural resistance to Salmonella typhimurium in different inbred mouse strains.
The mechanisms of natural resistance to intravenous challenge with Salmonella typhimurium C5 are complex. LD50 determinations… 
Highly Cited
1979
Highly Cited
1979
Inhibition of cis-platinum nephrotoxicity by diethyldithiocarbamate rescue in a rat model.
The nephrotoxic effects of cis-dichlorodiammineplatinum(II) (NSC-119875) administered to male F344 rats at the median lethal dose… 
Highly Cited
1976
Highly Cited
1976
A mechanism for cadmium- and zinc-induced tolerance to cadmium toxicity: involvement of metallothionein.
Highly Cited
1972
Highly Cited
1972
Teratogenicity of phthalate esters in rats.
In the past, it was demonstrated that small quantities of phthalates may be released from polyvinyl chloride items to… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)