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Lethal Dose 50

Known as: Dose 50, Lethal, Lethal Dose - 50%, LC-50 
The dose of a chemical or biologic preparation (e.g., a bacterial exotoxin or a suspension of bacteria) that is likely to cause death in 50% of the… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

drug potency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?
Gold nanoparticles have attracted enormous scientific and technological interest due to their ease of synthesis, chemical… 
Highly Cited
2006
Highly Cited
2006
Acute toxicological effects of copper nanoparticles in vivo.
Highly Cited
2005
Highly Cited
2005
A new approach to practical acute toxicity testing
  • D. Lorke
  • Archives of Toxicology
  • 2005
  • Corpus ID: 39225667
A method for the investigation of the acute toxicity of an unknown chemical substance, with an estimation on the LD50, is… 
Highly Cited
2001
Highly Cited
2001
Biotic ligand model of the acute toxicity of metals. 2. Application to acute copper toxicity in freshwater fish and Daphnia
The biotic ligand model (BLM) was developed to explain and predict the effects of water chemistry on the acute toxicity of metals… 
Review
1998
Review
1998
Review of the biological properties and toxicity of bee propolis (propolis).
  • G. Burdock
  • Food and chemical toxicology : an international…
  • 1998
  • Corpus ID: 28700702
Review
1998
Review
1998
The toxicology of microcystins.
  • R. Dawson
  • Toxicon : official journal of the International…
  • 1998
  • Corpus ID: 20202161
Highly Cited
1986
Highly Cited
1986
A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes.
Highly Cited
1985
Highly Cited
1985
Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin.
A highly specific polyclonal rabbit antiserum directed against murine cachectin/tumor necrosis factor (TNF) was prepared. When… 
Highly Cited
1984
Highly Cited
1984
Characteristics of gadolinium-DTPA complex: a potential NMR contrast agent.
Chelation of the rare-earth element gadolinium (Gd) with diethylenetriaminepentaacetic acid (DTPA) results in a strongly… 
Highly Cited
1952
Highly Cited
1952
Tables for Convenient Calculation of Median-Effective Dose (LD50 or ED50) and Instructions in their Use.
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