• Publications
  • Influence
Virulent Hessian Fly (Diptera: Cecidomyiidae) Larvae Induce a Nutritive Tissue During Compatible Interactions with Wheat
TLDR
The Hessian fly nutritive tissue probably acts as a sink tissue within the wheat seedling, benefiting the growth of larvae by importing photoassimilates, and is likely to be beneficial to R gene-defended plants. Expand
Comparative carcinogenicity in Sprague-Dawley rats of the polychlorinated biphenyl mixtures Aroclors 1016, 1242, 1254, and 1260.
TLDR
Liver toxicity was distinctly more severe in females than in males, and the incidence of hepatocellular neoplasms was highly sex-dependent, differed between Aroclor mixtures and, for females, increased with dose and followed the general incidence pattern. Expand
Chitin Degradation Proteins Produced by the Marine Bacterium Vibrio harveyi Growing on Different Forms of Chitin
TLDR
Six separate chitinase genes from V. harveyi appear to be unique based on DNA restriction patterns, immunological data, and enzyme activity, and this marine bacterium and probably others appear to synthesize separate Chitinases for efficient utilization of different forms of chit in and chitIn by-products. Expand
Impairment of thymus-dependent immune functions by exposure of the developing immune system to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
  • R. Faith, J. Moore
  • Biology, Medicine
  • Journal of toxicology and environmental health
  • 1 October 1977
TLDR
TCDD suppressed cell-mediated immune function without affecting humoral immune function and suppression of T-cell function was selective in that "helper" cell function was not suppressed. Expand
Examination of bone marrow, immunologic parameters and host susceptibility following pre- and postnatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
TLDR
Evidence was presented that depression of lymphoproliferative responses following mitogen stimulation in TCDD-immunosuppressed mice was due to a functional defect of lymphocyte activation rather than suppressor cell activity. Expand
Suppression of cellular immunity in rats and mice by maternal treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
  • J. Vos, J. Moore
  • Biology, Medicine
  • International archives of allergy and applied…
  • 1974
TLDR
In contrast to the marked effects in early life, reduced responsiveness of spleen cells to PHA in mice treated with TCDD when 1 month old was only seen at a dose level that was clearly toxic, and in 4-month-old mice, PHA responsiveness as well as GVH activity were not decreased. Expand
Increased susceptibility to bacterial infection as a sequela of exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
TLDR
The most important finding in this study is that extremely low levels of TCDD, which do not produce clinical or pathological change, still have the capacity to affect host defense. Expand
The effect of age and exposure duration on cancer induction by a known carcinogen in rats, mice, and hamsters.
TLDR
In all three rodent species an initial 12 month exposure to VC was adequate to detect its carcinogenic potential, but the shortened survival of VC exposed mice and hamsters precluded a meaningful comparison with longer periods of exposure. Expand
Comparative Carcinogenicity in Sprague-Dawley Rats of the Polychlorinated Biphenyl Mixtures Aroclors 1016, 1242, 1254, and 1260
TLDR
Liver toxicity was distinctly more severe in females than in males, and the incidence of hepatocellular neoplasms was highly sex-dependent (females > males), differed between Aroclor mixtures and, for females, increased with dose and followed the general incidence pattern. Expand
The comparative toxicity of chlorinated dibenzo-p-dioxins in mice and guinea pigs.
TLDR
At the toxic dose the spectrum and severity of lesions and organ weight effects were similar for all homologs and isomers within the same animal species; however, there were interspecies differences. Expand
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