Lens placode

Known as: Lens Placodes 
A pair of thickened surface ectodermal patches in the head region of the early embryo that will ultimately give rise to the lenses of the eyes.
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
Pax6 is a pivotal regulator of eye development throughout Metazoa, but the direct upstream regulators of vertebrate Pax6… (More)
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Highly Cited
2001
Highly Cited
2001
We describe experiments showing that fibroblast growth factor receptor (Fgfr) signaling plays a role in lens induction. Three… (More)
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Highly Cited
2000
Highly Cited
2000
The Pax6 transcription factor plays a key role in ocular development of vertebrates and invertebrates. Homozygosity of the Pax6… (More)
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Highly Cited
2000
Highly Cited
2000
In the mouse mutant dysgenetic lens (dyl) the lens vesicle fails to separate from the ectoderm, causing a fusion between the lens… (More)
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Highly Cited
2000
Highly Cited
2000
The development of neurogenic placodes in Xenopus laevis from the time of neural fold closure to larval stages is described… (More)
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Highly Cited
2000
Highly Cited
2000
Pax6 is a member of the mammalian Pax transcription factor family. Many of the Pax genes display semi-dominant loss-of-function… (More)
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Highly Cited
1999
Highly Cited
1999
Targeted inactivation of the Bmp7 gene in mouse leads to eye defects with late onset and variable penetrance (A. T. Dudley et al… (More)
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Highly Cited
1998
Highly Cited
1998
Activation of the first lens-specific gene of the chicken, delta 1-crystallin, is dependent on a group of lens nuclear factors… (More)
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Highly Cited
1998
Highly Cited
1998
After the vertebrate lens is induced from head ectoderm, lens-specific genes are expressed. Transcriptional regulation of the… (More)
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Highly Cited
1995
Highly Cited
1995
Small eye (Sey) mice homozygous for mutations in the Pax-6 gene have no lenses and no nasal cavities. We have examined the… (More)
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