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Lasalocid

Known as: Benzoic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methyl-, (2R-(2alpha(2S*(3R*,4S*,5S*,7R*),3S*,5S*),5alpha,6beta))-, Ionophore X 537A, Lasalocid A 
Cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. It… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (3)

Anti-Bacterial AgentsCoccidiostatsIonophores

Narrower (3)

AvatecX-537Abromolasalocid
In BloodIonophore activityLASALOCID SODIUM 90.7 g in 0.45 kg ORAL LIQUID [Bovatec 20]Lasalocid sodium

Papers overview

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1995
1995
Determination of lasalocid in eggs using liquid chromatography–electrospray mass spectrometry
A method is presented for the determination of the polyether ionophore, lasalocid, in eggs. Samples are extracted under acidic… 
1985
1985
Protein 4.1 is involved in a structural thermotropic transition of the red blood cell membrane detected by a spin-labeled stearic acid.
Proteins involved in a structural transition in red blood cell membranes detected at 8 +/- 1.5 degrees C by a stearic acid spin… 
Highly Cited
1983
Highly Cited
1983
Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations.
We examined the effects of the slow channel Ca++ blocker diltiazem on human platelet aggregation and TXA2 generation. Diltiazem… 
1983
1983
Some properties of the Ca2+-stimulated ATPase of a rat liver microsomal fraction.
1. The heavy microsomal fraction from rat liver apparently has very little Ca2+-stimulated ATPase activity, although it has an… 
1983
1983
Prostaglandin synthesis by human amnion is dependent upon extracellular calcium.
Prostaglandin (PG) E and F output was studied in collagenase-dispersed amnion cells to determine the effect of extracellular Ca2… 
1979
1979
Structure, synthesis and orientation of microfibrils. VI. The role of ions in microfibril deposition in Oocystis solitaria.
The action of a series of chelators, cryptates and ionophores on microfibril deposition and the presence of cortical microtubules… 
1977
1977
A comparison of the effects of phytohaemagglutinin and of calcium ionophore A23187 on the metabolism of glycerolipids in small lymphocytes.
1. The effects of phytohaemagglutinin and of a Ca2+ ionophore (A23187) on glycerolipid metabolism in lymphocytes from pig lymph… 
1976
1976
Some effects of ionophore A23187 on energy utilization and the distribution of cations and anions in mitochondria.
The effects of ionophore A23187 on the movements of Ca2+, Mg2+, H+ phosphate, and succinate and its effects on energy utilization… 
1975
1975
Anticoccidial activity of Lasalocid in control of moderate and severe coccidiosis.
The fermentation product lasalocid ("Antibiotic X-537A," Hoffmann-LaRoche) showed good anticoccidial activity when administered… 
1974
1974
Biosynthesis of lasalocid. III. Isolation and structure determination of four homologs of lasalocid A.
Four isomeric homologs of lasalocid A have been isolated from cultures of Streptomyces lasaliensis. The homologs each arise by…