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Lasalocid

Known as: Benzoic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methyl-, (2R-(2alpha(2S*(3R*,4S*,5S*,7R*),3S*,5S*),5alpha,6beta))-, Ionophore X 537A, Lasalocid A 
Cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. It… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (3)

Anti-Bacterial AgentsCoccidiostatsIonophores

Narrower (3)

AvatecX-537Abromolasalocid
In BloodIonophore activityLASALOCID SODIUM 90.7 g in 0.45 kg ORAL LIQUID [Bovatec 20]Lasalocid sodium

Papers overview

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Highly Cited
2012
Highly Cited
2012
Hydrogen sulfide donor sodium hydrosulfide-induced heat tolerance in tobacco (Nicotiana tabacum L) suspension cultured cells and involvement of Ca(2+) and calmodulin.
Highly Cited
1995
Highly Cited
1995
Calcium involvement in aminophospholipid exposure and microparticle formation during platelet activation: a study using Ca2+-ATPase inhibitors.
The development of procoagulant activity and microparticle formation during platelet activation is known to depend on an increase… 
Highly Cited
1994
Highly Cited
1994
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity.
Lipopolysaccharide (LPS)-stimulated mouse peritoneal macrophages produce large quantities of interleukin (IL)-1 beta but in the… 
Highly Cited
1989
Highly Cited
1989
L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor.
L-663,536 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2, 2-dimethylpropanoic acid) is a potent inhibitor of… 
Highly Cited
1984
Highly Cited
1984
Caffeine blocks activation of cyclic AMP synthesis in Dictyostelium discoideum.
Highly Cited
1981
Highly Cited
1981
Effects of lasalocid or monensin on lactate-producing or -using rumen bacteria.
Lasalocid or monensin inhibited most of the lactate-producing rumen bacteria (Butyrivibrio fibrisolvens, Eubacterium… 
Highly Cited
1979
Highly Cited
1979
Effect of Monensin and Lasalocid-Sodium on the Growth of Methanogenic and Rumen Saccharolytic Bacteria
It is thought that monensin increases the efficiency of feed utilization by cattle by altering the rumen fermentation. We studied… 
Highly Cited
1979
Highly Cited
1979
Inhibition of phosphatidylinositol synthesis and the inactivation of calcium entry after prolonged exposure of the blowfly salivary gland to 5-hydroxytryptamine.
The incorporation of [32P]Pi into all salivary-gland phospholipids except phosphatidic acid was inhibited by 5-hydroxytryptamine… 
Highly Cited
1978
Highly Cited
1978
The induction of the acrosome reaction in guinea-pig sperm by the divalent metal cation ionophore A23187.
The divalent metal cation ionophore A23187 induces an acrosome reaction in guinea-pig sperm which is dependent on external… 
Highly Cited
1976
Highly Cited
1976
Use of ionophore A23187 to measure cytoplasmic Ca buffering and activation of the Ca pump by internal Ca
DURING the formation of the mature mammalian erythrocyte, the reticulocyte sheds its nucleus, endoplasmic reticulum and… 
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