Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

Lactulose

Known as: 4-O-beta-D-Galactopyranosyl-D-fructose, 4-O-beta-D-Galactopyranosyl-D-fructofuranose, Lactulosum 
A disaccharide (sugar) synthesized from fructose and galactose, Lactulose is used to treat constipation and some liver diseases. Nondigestible in… 
National Institutes of Health

Related topics

Related topics

29 relations
Acidifying Activity [MoA]ConstipationDrug AllergyGalactosemias
Expand

Narrower (7)

AmivalexDuphalacEnuloseFZ 560
Expand

Broader (2)

DisaccharidesGastrointestinal Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Fiber and Prebiotics: Mechanisms and Health Benefits
The health benefits of dietary fiber have long been appreciated. Higher intakes of dietary fiber are linked to less… 
  • table 1
  • table 2
Review
2010
Review
2010
Lactulose versus Polyethylene Glycol for Chronic Constipation.
BACKGROUND Constipation is a common clinical problem. Lactulose and Polyethylene Glycol (PEG) are both commonly used osmotic… 
  • table 1
  • figure 1
  • figure 2
Highly Cited
2009
Highly Cited
2009
Secondary prophylaxis of hepatic encephalopathy: an open-label randomized controlled trial of lactulose versus placebo.
BACKGROUND & AIMS Hepatic encephalopathy (HE) is associated with a poor prognosis. Lactulose is used for the treatment of HE… 
Highly Cited
2007
Highly Cited
2007
Lactulose improves cognitive functions and health‐related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy
Minimal hepatic encephalopathy (MHE) has a negative effect on patients' daily functioning. Thus far, no study has investigated… 
Review
2006
Review
2006
Review article: prebiotics in the gastrointestinal tract
Prebiotics are short‐chain carbohydrates that alter the composition, or metabolism, of the gut microbiota in a beneficial manner… 
Review
2004
Review
2004
Dietary modulation of the human colonic microbiota: updating the concept of prebiotics
Prebiotics are non-digestible (by the host) food ingredients that have a beneficial effect through their selective metabolism in… 
Highly Cited
2003
Highly Cited
2003
Normalization of Lactulose Breath Testing Correlates With Symptom Improvement in Irritable Bowel Syndrome: A Double-Blind, Randomized, Placebo-Controlled Study
OBJECTIVE:We have recently found an association between abnormal lactulose breath test (LBT) findings and irritable bowel… 
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Highly Cited
2001
Highly Cited
2001
A comparative in vitro evaluation of the fermentation properties of prebiotic oligosaccharides
Aims: Comparison of in vitro fermentation properties of commercial prebiotic oligosaccharides. 
Highly Cited
2000
Highly Cited
2000
Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome.
BACKGROUND AND AIMS Post-dysenteric irritable bowel syndrome (PD-IBS) develops in up to 25% of patients following Campylobacter… 
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Highly Cited
1977
Highly Cited
1977
Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial.
A randomized double blind clinical comparison of neomycin and lactulose was performed in 33 cirrhotic patients with chronic… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE