Lac Operon

Known as: Lac Operons, Operons, Lactose, Operon, Lac 
The genetic unit consisting of three structural genes, an operator and a regulatory gene. The regulatory gene controls the synthesis of the three… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Transcriptional regulatory networks allow bacteria to express proteins only when they are needed. Adaptive hypotheses explaining… (More)
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Highly Cited
2007
Highly Cited
2007
The goal of systems biology is to understand the behavior of the whole in terms of knowledge of the parts. This is hard to… (More)
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Highly Cited
2003
Highly Cited
2003
Modeling has had a long tradition, and a remarkable success, in disciplines such as engineering and physics. In biology, however… (More)
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Highly Cited
2003
Highly Cited
2003
A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented. This model takes into… (More)
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Highly Cited
1997
Highly Cited
1997
A mathematical model of the lactose (lac) operon was developed to study diauxic growth on glucose and lactose. The model includes… (More)
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Highly Cited
1994
Highly Cited
1994
Repression of the lac promoter may be achieved in two different ways: either by interference with the action of RNA polymerase or… (More)
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Highly Cited
1990
Highly Cited
1990
We tested the effect of systematic destruction of all three lac operators of the chromosomal lac operon of Escherichia coli on… (More)
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Highly Cited
1984
Highly Cited
1984
The Escherichia coli lac operator has been placed on the 3' side of the promoter for the penicillinase gene of Bacillus… (More)
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Highly Cited
1983
Highly Cited
1983
Two hybrid promoters that are functional in Escherichia coli have been constructed. These hybrid promoters, tacI and tacII, were… (More)
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Highly Cited
1981
Highly Cited
1981
The use of gel electrophoresis for quantitative studies of DNA-protein interactions is described. This rapid and simple technique… (More)
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