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LYN protein, human

Known as: LYN, p53-LYN, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, human 
Tyrosine-protein kinase Lyn (512 aa, ~59 kDa) is encoded by the human LYN gene. This protein plays a role in tyrosine phosphorylation, signal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Tissue wounding induces the rapid recruitment of leukocytes. Wounds and tumours—a type of ‘unhealed wound’—generate hydrogen… Expand
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Highly Cited
2010
Highly Cited
2010
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is… Expand
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Highly Cited
2009
Highly Cited
2009
Src-family tyrosine kinases (SFKs), which participate in a variety of signal transduction events, are known to localize to the… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Imatinib is a tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia (CML). BCR-ABL mutations… Expand
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Highly Cited
2008
Highly Cited
2008
Neuropathic pain, a debilitating chronic pain following nerve damage, is a reflection of the aberrant functioning of a… Expand
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Highly Cited
2000
Highly Cited
2000
Activation of platelets by collagen is mediated by the complex glycoprotein VI (GPVI)/Fc receptor gamma (FcR gamma chain). In the… Expand
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Highly Cited
1999
Highly Cited
1999
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. The ionotropic glutamate receptors… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND To elucidate the role of the Src family kinase Lyn in B cell receptor (BCR) signaling, we and others previously… Expand
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Highly Cited
1995
Highly Cited
1995
Mice homozygous for a disruption at the Lyn locus display abnormalities associated with the B lymphocyte lineage and in mast cell… Expand
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Highly Cited
1992
Highly Cited
1992
THE high-affinity IgE receptor (FcɛRI), which is expressed on the surface of mast cells and basophils, has a central role in… Expand
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