LYN protein, human

Known as: LYN, p53-LYN, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, human 
Tyrosine-protein kinase Lyn (512 aa, ~59 kDa) is encoded by the human LYN gene. This protein plays a role in tyrosine phosphorylation, signal… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
05101519922018

Papers overview

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2015
2015
Microglia, the resident immune cells of the brain, have been shown to display a complex spectrum of roles that span from… (More)
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2014
2014
The transmembrane adaptor protein PAG/CBP (here, PAG) is expressed in multiple cell types. Tyrosine-phosphorylated PAG serves as… (More)
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Highly Cited
2010
Highly Cited
2010
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is… (More)
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2009
2009
We targeted LYN, a src-tyosine kinase involved in B-cell activation, in case–control association studies using populations of… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Imatinib is a tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia (CML). BCR-ABL mutations… (More)
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Highly Cited
2003
Highly Cited
2003
Clinical studies have shown that the tyrosine kinase inhibitor STI571 effectively controls BCR-ABL-positive chronic myelogenous… (More)
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1999
1999
The cAMP-specific phosphodiesterase (PDE) HSPDE 4A4B(pde46) selectively bound SH3 domains of SRC family tyrosyl kinases. Such an… (More)
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1999
1999
Although nitric oxide (NO) has potent antiplatelet actions, the signaling pathways affected by NO in the platelet are poorly… (More)
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1998
1998
Exposure of B-lineage lymphoid cells to ionizing radiation induces an elevation of c-jun proto-oncogene mRNA levels. This signal… (More)
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1992
1992
The lymphokine interleukin-3 (IL-3) promotes the growth and survival of immature hematopoietic cells. Previous studies have shown… (More)
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