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LY 355703
Known as:
LY-355703
, LY355703
National Institutes of Health
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1 relation
Broader (1)
cryptophycin 52
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Abstract LB-053: Towards new cryptophycins as promising payloads for ADC
Brun Marie-Priscille
,
H. Bouchard
,
+16 authors
I. Sassoon
2016
Corpus ID: 78232400
Cryptophycins are a class of macrocyclic depsipeptides produced as secondary metabolites by cyanobacteria of the genus Nostoc and…
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2005
2005
A multi-center phase II study of the cryptophycin analogue LY355703 in patients with platinum-resistant ovarian cancer
G. D'Agostino
,
J. D. Campo
,
+6 authors
G. Scambia
2005
Corpus ID: 74408848
5097 Background: LY355703 is a synthetic product structurally related to the cryptophycin family isolated from the blue-green…
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2004
2004
Biological evaluation of cryptophycin 52 fragment A analogues: effect of the multidrug resistance ATP binding cassette transporters on antitumor activity.
R. Al-Awar
,
T. Corbett
,
+4 authors
Daniel C Williams
Molecular Cancer Therapeutics
2004
Corpus ID: 23858133
Cryptophycin 52 (LY355703) is a potent antiproliferative analogue of the marine natural product cryptophycin 1. It has been shown…
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2002
2002
Phase I trial of the cryptophycin analogue LY355703 administered as an intravenous infusion on a day 1 and 8 schedule every 21 days.
J. Stevenson
,
Weijing Sun
,
+9 authors
P. O'dwyer
Clinical Cancer Research
2002
Corpus ID: 14377874
The cryptophycin analogue LY355703 is a potent inhibitor of microtubule polymerization that displays in vitro and in vivo…
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2001
2001
A phase II study of LY355703 (cryptophycine) as first-line therapy for stage IIIb or IV NSCLC subjects: preliminary analysis
G. Groth
,
K. Schott
,
U. Ohnmacht
,
C. Manegold
,
U. Gatzemeier
2001
Corpus ID: 72326520
2000
2000
Acute vulvar vestibulitis occurring during chemotherapy with cryptophycin analogue LY355703.
T. D. De Pas
,
M. Mandalà
,
G. Curigliano
,
F. Peccatori
Obstetrics and Gynecology
2000
Corpus ID: 2434676
2000
2000
Antitumor activity of cryptophycins: effect of infusion time and combination studies
K. Menon
,
E. Álvarez
,
+5 authors
B. Teicher
Cancer Chemotherapy and Pharmacology
2000
Corpus ID: 20467131
Introduction/Purpose: Cryptophycins are a family of antitubulin antitumor agents. A synthetic cryptophycin derivative (LY355703…
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2000
2000
Antineoplastic therapy with LY 355703 has been associated with acute vulval vestibulitis
2000
Corpus ID: 195102277
1998
1998
Determination of LY355703 in dog and mouse plasma by positive ion liquid chromatography/tandem mass spectrometry with atmospheric pressure chemical ionization.
M. Berna
,
R. Shugert
,
J. Mullen
Journal of Mass Spectrometry
1998
Corpus ID: 19150116
A liquid chromatographic/mass spectrometric assay was developed for the determination of LY355703, a potent anti-tumor drug, in…
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1998
1998
Binding of the epoxide cryptophycin analog, LY355703 to albumin and its effect on in vitro antiproliferative activity.
R. Schultz
,
C. Shih
,
P. Wood
,
S. Harrison
,
W. Ehlhardt
Oncology Report
1998
Corpus ID: 42838611
Cryptophycin, isolated from the cyanobacterium Nostoc, is a cytotoxic dioxadiazacyclohexadecenetetrone which causes rapid…
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