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LY 294002

Known as: LY-294002, LY294002 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Phosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in cancer. By applying mass spectroscopy-based sequencing… Expand
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Highly Cited
2005
Highly Cited
2005
PIK3CA is mutated in diverse human cancers, but the functional effects of these mutations have not been defined. To evaluate the… Expand
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Highly Cited
2005
Highly Cited
2005
The mammalian target of rapamycin (mTOR) has emerged as an important cancer therapeutic target. Rapamycin and its derivatives… Expand
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Highly Cited
2005
Highly Cited
2005
Glucagon-like peptide 1 (GLP-1), a gut incretin hormone that stimulates insulin secretion, also activates antiapoptotic signaling… Expand
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Highly Cited
2004
Highly Cited
2004
H2AX phosphorylation is an early step in the response to DNA damage. It is widely accepted that ATM (ataxia telangiectasia… Expand
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Highly Cited
2004
Highly Cited
2004
Adiponectin is an adipocyte-specific adipocytokine with anti-atherogenic and anti-diabetic properties. Here, we investigated… Expand
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Highly Cited
2001
Highly Cited
2001
Estrogen receptors (ERs) mediate most of the biological effects of estrogen in mammary and uterine epithelial cells by binding to… Expand
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Highly Cited
2000
Highly Cited
2000
In our previous study we showed that insulin-like growth factor-I induces a cAMP-response element (CRE) site-containing Bcl-2… Expand
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Highly Cited
1998
Highly Cited
1998
Vascular endothelial growth factor (VEGF) has been found to have various functions on endothelial cells, the most prominent of… Expand
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Highly Cited
1994
Highly Cited
1994
Phosphatidylinositol (PtdIns) 3-kinase is an enzyme implicated in growth factor signal transduction by associating with receptor… Expand
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