LY 294002

Known as: LY-294002, LY294002 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
020040019902018

Papers overview

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Highly Cited
2008
Highly Cited
2008
Phosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in cancer. By applying mass spectroscopy-based sequencing… (More)
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Highly Cited
2005
Highly Cited
2005
The mammalian target of rapamycin (mTOR) has emerged as an important cancer therapeutic target. Rapamycin and its derivatives… (More)
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Highly Cited
2004
Highly Cited
2004
H2AX phosphorylation is an early step in the response to DNA damage. It is widely accepted that ATM (ataxia telangiectasia… (More)
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Highly Cited
2001
Highly Cited
2001
To evaluate the role of Akt/PKB in non-small cell lung cancer (NSCLC) survival, we analyzed NSCLC cell lines that differed in… (More)
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Highly Cited
2001
Highly Cited
2001
Estrogen receptors (ERs) mediate most of the biological effects of estrogen in mammary and uterine epithelial cells by binding to… (More)
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Highly Cited
2000
Highly Cited
2000
Dysregulated signal transduction from receptor tyrosine kinases to phosphatidylinositol 3-kinase (PI3K), AKT (protein kinase B… (More)
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Highly Cited
2000
Highly Cited
2000
We have studied the role of phosphatidylinositol 3-OH kinase (PI3K)-Akt signaling in transforming growth factor beta (TGFbeta… (More)
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Highly Cited
1999
Highly Cited
1999
Ovarian cancer is the leading cause of death from gynecological malignancy and the fourth leading cause of cancer death among… (More)
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Highly Cited
1995
Highly Cited
1995
Nerve growth factor (NGF) induces both differentiation and survival of neurons by binding to the Trk receptor protein tyrosine… (More)
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Highly Cited
1994
Highly Cited
1994
Phosphatidylinositol (PtdIns) 3-kinase is an enzyme implicated in growth factor signal transduction by associating with receptor… (More)
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