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LY 2140023

Known as: LY-2140023, LY2140023 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BackgroundPomaglumetad methionil (LY2140023 monohydrate) is a potent and highly selective agonist for the metabotropic glutamate… Expand
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Review
2013
Review
2013
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to… Expand
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Highly Cited
2013
Highly Cited
2013
BackgroundWe compared the time to discontinuation due to lack of tolerability over 24 weeks in patients suffering from… Expand
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Highly Cited
2013
Highly Cited
2013
This study tested whether treatment with pomaglumetad methionil (LY2140023 monohydrate), a metabotropic glutamate receptor 2/3… Expand
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Review
2012
Review
2012
Schizophrenia is a devastating chronic psychotic disorder characterized by positive, negative, and cognitive symptoms. Although… Expand
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Highly Cited
2011
Highly Cited
2011
The primary objective of this study was to test the hypothesis that 1 or more dose levels of LY2140023 monohydrate, an oral… Expand
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2010
2010
LY-2140023 is a methionine amide prodrug of the orthosteric metabotropic glutamate receptor (mGluR)2/3 agonist LY-404039, being… Expand
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Highly Cited
2008
Highly Cited
2008
(–)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039) is a potent and selective group II… Expand
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2008
2008
In recent years, evidence has been accumulating indicating a major role of glutamate in the pathogenesis and pathophysiology of… Expand
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Highly Cited
2007
Highly Cited
2007
Schizophrenia is a chronic, complex and heterogeneous mental disorder, with pathological features of disrupted neuronal… Expand
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