LY 2140023

Known as: LY-2140023, LY2140023 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to… (More)
  • figure 1
  • figure 2
Is this relevant?
2013
2013
This study tested whether treatment with pomaglumetad methionil (LY2140023 monohydrate), a metabotropic glutamate receptor 2/3… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2013
2013
Pomaglumetad methionil (LY2140023 monohydrate, hereafter referred to as LY2140023) is currently in clinical development as a… (More)
Is this relevant?
Review
2012
Review
2012
Schizophrenia is a devastating chronic psychotic disorder characterized by positive, negative, and cognitive symptoms. Although… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2011
Highly Cited
2011
The primary objective of this study was to test the hypothesis that 1 or more dose levels of LY2140023 monohydrate, an oral… (More)
  • table 1
Is this relevant?
2010
2010
LY-2140023 is a methionine amide prodrug of the orthosteric metabotropic glutamate receptor (mGluR)2/3 agonist LY-404039, being… (More)
Is this relevant?
Review
2010
Review
2010
Metabotropic glutamate receptors (mGlu receptors), with their unique signaling systems and pharmacological characteristics, have… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
(-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039) is a potent and selective group II… (More)
Is this relevant?
Review
2008
Review
2008
Schizophrenia is a debilitating lifelong disorder affecting up to 1% of the population worldwide, producing significant financial… (More)
  • table 1
  • figure 1
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Schizophrenia is a chronic, complex and heterogeneous mental disorder, with pathological features of disrupted neuronal… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
Is this relevant?