LY 171555

 
National Institutes of Health

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1994
1994
No direct correlation between behaviorally active doses of the dopamine D2 agonist LY 171555 and displacement of [123I]IBZM as measured with SPECT in MPTP monkeys.
Almost no information is available concerning the link between clinical effects of dopamine D2 receptor agonists in the treatment… (More)
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Highly Cited
1993
Highly Cited
1993
Relative roles of ventral striatal D1 and D2 dopamine receptors in responding with conditioned reinforcement
Several experiments investigated the involvement of D1 and D2 dopamine receptors in the ventral striatum in the control over… (More)
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Highly Cited
1992
Highly Cited
1992
Long-term synaptic depression in the striatum: physiological and pharmacological characterization.
The effect of tetanic activation of corticostriatal glutamatergic fibers was studied in striatal slices by utilizing… (More)
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1991
1991
Anticonvulsant effects of ipsilateral but not contralateral microinjections of the dopamine D2 agonist LY 171555 into the nucleus accumbens of amygdala-kindled rats.
Recent radioligand binding studies demonstrated an increase in the density of dopamine D2 receptors in the nucleus accumbens… (More)
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1990
1990
LY 171555-induced catalepsy and defensive behavior in four strains of mice suggest the involvement of different D2 dopamine receptor systems
The D2 dopamine receptor agonist LY 171555 (0.5 to 5 mg/kg) induces dose-dependent catalepsy in C57BL/6, DBA/2 and BALB/c inbred… (More)
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1989
1989
Reversal of a mecamylamine-induced cognitive deficit with the D2 agonist, LY 171555.
Pharmacological blockade of either nicotinic or muscarinic cholinergic receptors has been found to impair choice accuracy in the… (More)
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1989
1989
Genotype-dependent modulation of LY 171555-induced defensive behavior in the mouse
The selective D2 dopamine receptor agonist LY 171555 increased defensive behavior dose dependently, decreased social… (More)
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1989
1989
Behavioural synergism between the dopamine agonists SKF 38393 and LY 171555 in dopamine-depleted mice: Antagonism by sulpiride reveals only stimulant postsynaptic D-2 receptors
The behavioural effects of the D-1 agonist SKF 38393 (0.56-45 mg/kg) and the D-2 agonist LY 171555 (0.05-6.25 mg/kg) were studied… (More)
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1988
1988
Enhancement by the D1 dopamine agonist SKF 38393 of specific components of stereotypy elicited by the D2 agonists LY 171555 and RU 24213.
Dose-effect curves were obtained for five specific components of stereotyped behavior (locomotor hyperactivity, rearing, sniffing… (More)
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1988
1988
The D1 agonist SKF 38393 inhibits the antiparkinsonian activity of the D2 agonist LY 171555 in the MPTP-treated marmoset.
Administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to common marmosets induced persistent motor deficits… (More)
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