LRRK2 gene

Known as: RIPK7, Leucine-Rich Repeat Kinase 2 Gene, DARDARIN 
This protein may play a role in the modulation of protein phosphorylation.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Studies of Parkinson's disease (PD) have been hindered by lack of access to affected human dopaminergic (DA) neurons. Here, we… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Parkinson's disease (PD). The… (More)
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Highly Cited
2007
Highly Cited
2007
Mutations in the LRRK2 (leucine-rich repeat kinase-2) gene cause late-onset PD (Parkinson's disease). LRRK2 contains leucine-rich… (More)
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Highly Cited
2007
Highly Cited
2007
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) cause late-onset Parkinson's disease indistinguishable from idiopathic… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in LRRK2 underlie an autosomal-dominant, inherited form of Parkinson's disease (PD) that mimics the clinical features… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in the the leucine-rich repeat kinase-2 (LRRK2) gene cause autosomal-dominant Parkinson disease and some cases of… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in the LRRK2 gene have been identified in families with autosomal dominant parkinsonism. We amplified and sequenced the… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been shown to cause autosomal dominant Parkinson's disease. Few… (More)
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Highly Cited
2005
Highly Cited
2005
Parkinson's disease (PD) is a disorder of movement, cognition, and emotion, and it is characterized pathologically by neuronal… (More)
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Highly Cited
2004
Highly Cited
2004
We have previously linked families with autosomal-dominant, late-onset parkinsonism to chromosome 12p11.2-q13.1 (PARK8). By high… (More)
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