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LRRK2 gene

Known as: RIPK7, Leucine-Rich Repeat Kinase 2 Gene, DARDARIN 
This protein may play a role in the modulation of protein phosphorylation.
National Institutes of Health

Related topics

Related topics

7 relations
LRRK1 geneLRRK2 wt AlleleLeucine-Rich Repeat Serine/Threonine-Protein Kinase 2, humanParkinson Disease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers
Missense mutations in the leucine-rich repeat kinase 2 (LRRK2) gene can cause late-onset Parkinson disease (PD). LRRK2 mutations… 
2012
2012
Cerebrospinal fluid amyloid β and tau in LRRK2 mutation carriers
Objective: The goal of the current investigation was to examine a cohort of symptomatic and asymptomatic LRRK2 mutation carriers… 
2009
2009
Prevalence and clinical features of LRRK2 mutations in patients with Parkinson’s disease in southern Spain
Background and purpose: Mutations in leucine‐rich repeat kinase 2 (LRRK2) gene are associated with both familial and idiopathic… 
2009
2009
Lrrk2 interaction with alpha-synuclein in diffuse Lewy body disease.
2007
2007
Comprehensive Screening of a North American Parkinson’s Disease Cohort for LRRK2 Mutation
Background: Recently, mutations in LRRK2 encoding the protein dardarin have been linked to an autosomal dominant form of… 
Highly Cited
2006
Highly Cited
2006
Recurrent LRRK2 (Park8) mutations in early‐onset Parkinson's disease
Mutations in LRRK2 (leucine‐rich repeat kinase 2) have been associated with autosomal dominant Parkinson's disease (PD) and… 
Highly Cited
2006
Highly Cited
2006
Lack of G2019S LRRK2 mutation in a cohort of Taiwanese with sporadic Parkinson's disease
Mutations in the leucine‐rich repeat kinase 2 (LRRK2) gene have been shown to cause autosomal dominant and sporadic Parkinson's… 
Highly Cited
2006
Highly Cited
2006
LRRK2 mutations are a common cause of Parkinson's disease in Spain
Pathogenic mutations in the leucine‐rich repeat kinase 2 gene (LRRK2; PARK8) have been implicated in autosomal dominant, late… 
2005
2005
Altered α-synuclein homeostasis causing Parkinson's disease: the potential roles of dardarin
2005
2005
LRRK2 mutations are not common in Alzheimer's disease
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