Skip to search formSkip to main contentSkip to account menu

LMX1B gene

Known as: LIM Homeobox Transcription Factor 1, Beta Gene, LIM HOMEOBOX TRANSCRIPTION FACTOR 1, BETA, LMX1B 
This gene plays a role in both transcriptional regulation and the mediation of limb development.
National Institutes of Health

Related topics

Related topics

8 relations
Cell Differentiation processHomo sapiensLIM homeobox transcription factor 1 betaLimb Development

Narrower (1)

LMX1B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
LMX1B mutations cause hereditary FSGS without extrarenal involvement.
LMX1B encodes a homeodomain-containing transcription factor that is essential during development. Mutations in LMX1B cause nail… 
Highly Cited
2005
Highly Cited
2005
Genotype–phenotype studies in nail-patella syndrome show that LMX1B mutation location is involved in the risk of developing nephropathy
Nail-patella syndrome (NPS) is characterized by developmental defects of dorsal limb structures, nephropathy, and glaucoma and is… 
Highly Cited
2003
Highly Cited
2003
Lmx1b is essential for the development of serotonergic neurons
The specification and differentiation of serotonergic (5-HT) neurons require both extrinsic signaling molecules and intrinsic… 
Review
2003
Review
2003
Nail patella syndrome: a review of the phenotype aided by developmental biology
Nail patella syndrome (NPS) is an autosomal dominant condition affecting the nails, skeletal system, kidneys, and eyes. Skeletal… 
Highly Cited
2003
Highly Cited
2003
Lmx1b, Pet-1, and Nkx2.2 Coordinately Specify Serotonergic Neurotransmitter Phenotype
Serotonergic (5-HT) neurons in the brainstem modulate a wide range of physiological processes and behaviors. Two transcription… 
Highly Cited
2000
Highly Cited
2000
A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b
We identified the LIM homeodomain transcription factor Lmx1b in the mesencephalic dopamine (mesDA) systems of embryos and adults… 
Highly Cited
2000
Highly Cited
2000
lmx1b, a LIM homeodomain class transcription factor, is necessary for normal development of multiple tissues in the anterior segment of the murine eye
Summary: Proper development of the anterior segment of the mammalian eye is critical for normal ocular function. Indeed, several… 
Highly Cited
1998
Highly Cited
1998
Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome
Dorsal-ventral limb patterning in vertebrates is thought to be controlled by the LIM-homeodomain protein Lmx1b which is expressed… 
Highly Cited
1998
Highly Cited
1998
Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome.
Nail-patella syndrome (NPS) is an inherited developmental disorder most commonly involving maldevelopment of the fingernails… 
Highly Cited
1998
Highly Cited
1998
Mutation analysis of LMX1B gene in nail-patella syndrome patients.
Nail-patella syndrome (NPS), a pleiotropic disorder exhibiting autosomal dominant inheritance, has been studied for >100 years… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)