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LLGL1 wt Allele

Known as: LLGL, HUGL, HUGL1 
Human LLGL1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 19 kb in length. This allele, which encodes lethal(2) giant… 
National Institutes of Health

Related topics

Related topics

9 relations
17p11.2Cell MovementCytokinesisCytoskeletal Modeling

Broader (1)

LLGL1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
DNA methylation of DLG4 and GJA-1 of human hippocampus and prefrontal cortex in major depression is unchanged in comparison to healthy individuals
2015
2015
Hugl-1 inhibits glioma cell growth in intracranial model
Drosophila lethal (2) giant larvae (lgl) has been reported as a tumor suppressor and could regulate the Drosophila hippo… 
2012
2012
Preservation of HUGL-1 expression as a favourable prognostic factor in pancreatic carcinoma.
AIM The expression of the human homologue of Drosophila tumour suppressor gene lgl (HUGL-1) in pancreatic cancer was… 
2011
2011
Phenotypes associated with Saccharomyces cerevisiae Hug1 protein, a putative negative regulator of dNTP Levels, reveal similarities and differences with sequence-related dif1
Saccharomyces cerevisiae Hugl is a small protein of unknown function that is highly inducible following replication stress and… 
2008
2008
Regulation of the hDlg/hScrib/Hugl-1 tumour suppressor complex.
2007
2007
Fine mapping of a linkage region on chromosome 17p13 reveals that GABARAP and DLG4 are associated with vulnerability to nicotine dependence in European-Americans.
A two-stage association study was conducted targeting a genomic region on chromosome 17p13 that we reported likely to harbor… 
2007
2007
E 6 AP-Dependent Degradation of DLG 4 / PSD 95 by High-Risk Human Papillomavirus Type 18 E 6 Protein
In most cervical cancers, DNAs of high-risk mucosotropic human papillomaviruses (HPVs), such as types 16 and 18, are maintained… 
Highly Cited
2006
Highly Cited
2006
Expression of Hugl-1 is strongly reduced in malignant melanoma
The human gene Hugl-1 (Llgl/Lgl1) has significant homology to the Drosophila tumor suppressor gene lethal(2)giant larvae (lgl… 
2004
2004
Uplink to downlink spatial covariance matrix transformation methods for downlink beamforming of a UMTS-FDD system
We analyze the effect of different uplink to downlink spatial covariance transformation methods on the system level performance… 
Highly Cited
1995
Highly Cited
1995
A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain.
Inactivation of the tumour suppressor gene lethal(2) giant larvae (D-lgl) of Drosophila leads to malignant transformation of the… 
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