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LLGL1 wt Allele

Known as: LLGL, HUGL, HUGL1 
Human LLGL1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 19 kb in length. This allele, which encodes lethal(2) giant… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Preterm birth places infants in an adverse environment that leads to abnormal brain development and cerebral injury through a… Expand
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2013
2013
Opioid drugs are highly addictive and their abuse has a strong genetic load. Dopamine–glutamate interactions are hypothesized to… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Research is increasingly linking autism spectrum disorders and other neurodevelopmental disorders to synaptic… Expand
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2009
2009
Purpose: Lethal giant larvae functions as a cell polarity regulator and a tumor suppressor in Drosophila. Its evolutionary… Expand
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2008
2008
The proper function of the Scribble tumour suppressor complex is dependent upon the correct localisation of its components… Expand
Highly Cited
2006
Highly Cited
2006
ABSTRACT In most cervical cancers, DNAs of high-risk mucosotropic human papillomaviruses (HPVs), such as types 16 and 18, are… Expand
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Highly Cited
2006
Highly Cited
2006
The human gene Hugl-1 (Llgl/Lgl1) has significant homology to the Drosophila tumor suppressor gene lethal(2)giant larvae (lgl… Expand
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Highly Cited
2005
Highly Cited
2005
The human gene, human giant larvae (Hugl-1/Llg1/Lgl1) has significant homology to the Drosophila tumour suppressor gene lethal(2… Expand
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1997
1997
We have determined the cDNA sequence, expression pattern, and chromosomal location of the human gene DLG4, encoding the… Expand
Highly Cited
1995
Highly Cited
1995
Inactivation of the tumour suppressor gene lethal(2) giant larvae (D-lgl) of Drosophila leads to malignant transformation of the… Expand