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LLGL1 wt Allele
Known as:
LLGL
, HUGL
, HUGL1
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Human LLGL1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 19 kb in length. This allele, which encodes lethal(2) giant…
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National Institutes of Health
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Related topics
Related topics
9 relations
17p11.2
Cell Movement
Cytokinesis
Cytoskeletal Modeling
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Broader (1)
LLGL1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants
Michelle L. Krishnan
,
Juliette van Steenwinckel
,
+18 authors
P. Gressens
Nature Communications
2017
Corpus ID: 21420402
Preterm birth places infants in an adverse environment that leads to abnormal brain development and cerebral injury through a…
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Highly Cited
2010
Highly Cited
2010
Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome.
M. Feyder
,
Rose-Marie Karlsson
,
+18 authors
A. Holmes
The American journal of psychiatry
2010
Corpus ID: 535850
OBJECTIVE Research is increasingly linking autism spectrum disorders and other neurodevelopmental disorders to synaptic…
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Highly Cited
2009
Highly Cited
2009
Aberrant Splicing of Hugl-1 Is Associated with Hepatocellular Carcinoma Progression
Xuefeng Lu
,
Xiujing Feng
,
+10 authors
Zhengjun Chen
Clinical Cancer Research
2009
Corpus ID: 10566643
Purpose: Lethal giant larvae functions as a cell polarity regulator and a tumor suppressor in Drosophila. Its evolutionary…
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2008
2008
Regulation of the hDlg/hScrib/Hugl-1 tumour suppressor complex.
P. Massimi
,
N. Narayan
,
+4 authors
L. Banks
Experimental cell research
2008
Corpus ID: 45232934
2007
2007
Fine mapping of a linkage region on chromosome 17p13 reveals that GABARAP and DLG4 are associated with vulnerability to nicotine dependence in European-Americans.
X. Lou
,
Jennie Z. Ma
,
Dongxiao Sun
,
T. Payne
,
Ming D. Li
Human molecular genetics
2007
Corpus ID: 14595849
A two-stage association study was conducted targeting a genomic region on chromosome 17p13 that we reported likely to harbor…
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Highly Cited
2006
Highly Cited
2006
Expression of Hugl-1 is strongly reduced in malignant melanoma
S. Kuphal
,
S. Wallner
,
+5 authors
A. Bosserhoff
Oncogene
2006
Corpus ID: 9808205
The human gene Hugl-1 (Llgl/Lgl1) has significant homology to the Drosophila tumor suppressor gene lethal(2)giant larvae (lgl…
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Highly Cited
2006
Highly Cited
2006
E6AP-Dependent Degradation of DLG4/PSD95 by High-Risk Human Papillomavirus Type 18 E6 Protein
K. Handa
,
T. Yugawa
,
M. Narisawa-Saito
,
S. Ohno
,
M. Fujita
,
T. Kiyono
Journal of Virology
2006
Corpus ID: 31723457
ABSTRACT In most cervical cancers, DNAs of high-risk mucosotropic human papillomaviruses (HPVs), such as types 16 and 18, are…
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Highly Cited
2005
Highly Cited
2005
Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer
C. Schimanski
,
G. Schmitz
,
+8 authors
D. Strand
Oncogene
2005
Corpus ID: 37967156
The human gene, human giant larvae (Hugl-1/Llg1/Lgl1) has significant homology to the Drosophila tumour suppressor gene lethal(2…
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Highly Cited
1997
Highly Cited
1997
Human postsynaptic density-95 (PSD95): location of the gene (DLG4) and possible function in nonneural as well as in neural tissues.
D. G. Stathakis
,
K. Hoover
,
Z. You
,
P. Bryant
Genomics
1997
Corpus ID: 8876021
We have determined the cDNA sequence, expression pattern, and chromosomal location of the human gene DLG4, encoding the…
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Highly Cited
1995
Highly Cited
1995
A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain.
D. Strand
,
S. Unger
,
+7 authors
J. Coy
Oncogene
1995
Corpus ID: 6726396
Inactivation of the tumour suppressor gene lethal(2) giant larvae (D-lgl) of Drosophila leads to malignant transformation of the…
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