Skip to search formSkip to main contentSkip to account menu

LILRB1 gene

Known as: MIR-7, MIR7, ILT2 
This gene is involved in binding to class I MHC antigens.
National Institutes of Health

Related topics

Related topics

4 relations
Immune responseLILRB1 protein, humanLigand BindingReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Functions of Immune Checkpoint Molecules Beyond Immune Evasion.
Immune checkpoint molecules, including inhibitory and stimulatory immune checkpoint molecules, are defined as ligand-receptor… 
Highly Cited
2017
Highly Cited
2017
An isolate of Vibrio campbellii carrying the pirVP gene causes acute hepatopancreatic necrosis disease
Emerging Microbes & Infections (2017) 6, e2; doi:10.1038/emi.2016.131; published online 4 January 2017 
Highly Cited
2012
Highly Cited
2012
Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors
The non-classical Human leukocyte antigen G (HLA-G) differs from classical HLA class I molecules by its low genetic diversity, a… 
Highly Cited
2011
Highly Cited
2011
HLA Class I Allelic Sequence and Conformation Regulate Leukocyte Ig-Like Receptor Binding
Leukocyte Ig-like receptors (LILRs) are a family of innate immune receptors predominantly expressed by myeloid cells that can… 
Highly Cited
2010
Highly Cited
2010
Influence of human cytomegalovirus infection on the NK cell receptor repertoire in children
Human cytomegalovirus (hCMV) infection is usually asymptomatic but may cause disease in immunocompromised hosts. It has been… 
Highly Cited
2009
Highly Cited
2009
HLA-G homodimer-induced cytokine secretion through HLA-G receptors on human decidual macrophages and natural killer cells
Human decidual CD14+ macrophages and CD56+ NK cells were isolated from material obtained after first-trimester pregnancy… 
2008
2008
Rapamycin downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 induction.
Highly Cited
2007
Highly Cited
2007
The Human Cytomegalovirus MHC Class I Homolog UL18 Inhibits LIR-1+ but Activates LIR-1− NK Cells1
The inhibitory leukocyte Ig-like receptor 1 (LIR-1, also known as ILT2, CD85j, or LILRB1) was identified by its high affinity for… 
Highly Cited
2007
Highly Cited
2007
Interaction of HLA‐B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA‐B27 heterotrimers, is independent of the sequence of bound peptide
HLA‐B27 can form beta‐2 microglobulin (β2m)‐associated heterotrimers (HLA‐B27) and β2m‐free homodimers (B272). Here, we study the… 
Highly Cited
2006
Highly Cited
2006
Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
HLA-G is a nonclassical MHC class I (MHCI) molecule that can suppress a wide range of immune responses in the maternal–fetal… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)