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LGALS8 protein, human

Known as: Galectin 8, Prostate Carcinoma Tumor Antigen 1, PO66-CBP 
Galectin-8 (317 aa, ~36 kDa) is encoded by the human LGALS8 gene. This protein is involved in cell adhesion and carbohydrate binding.
National Institutes of Health

Related topics

Related topics

14 relations
ApoptosisBinding ProteinsCell AdhesionCell Cycle Control

Broader (3)

Galactose Binding LectinLectinPhytohemagglutinins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Galectins Control mTOR in Response to Endomembrane Damage.
Highly Cited
2010
Highly Cited
2010
Innate immune lectins kill bacteria expressing blood group antigen
The expression of ABO(H) blood group antigens causes deletion of cells that generate self-specific antibodies to these antigens… 
Highly Cited
2007
Highly Cited
2007
Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface.
Galectin-8 has two different carbohydrate recognition domains (CRDs), the N-terminal Gal-8N and the C-terminal Gal-8C linked by a… 
Highly Cited
2006
Highly Cited
2006
Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells.
Galectins are implicated in a large variety of biological functions, many of which depend on their carbohydrate-binding ability… 
Highly Cited
2003
Highly Cited
2003
Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting
Knowledge of the expression of the galectins in human colon carcinomas is mainly restricted to galectin‐3 and, to a lesser extent… 
Highly Cited
2001
Highly Cited
2001
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures
Purpose: Knowledge about galectin expression by human tumor cells is mainly restricted to galectins-1 and -3. This study was… 
Highly Cited
2001
Highly Cited
2001
Galectins Are Differentially Expressed in Supratentorial Pilocytic Astrocytomas, Astrocytomas, Anaplastic Astrocytomas and Glioblastomas, and Significantly Modulate Tumor Astrocyte Migration
Galectins, a family of mammalian lectins with specificity to β‐galactosides, are involved in growth‐regulatory mechanisms and… 
Highly Cited
2001
Highly Cited
2001
Galectin-8 Functions as a Matricellular Modulator of Cell Adhesion*
The interaction of cells with the extracellular matrix regulates cell adhesion and motility. Here we demonstrate that different… 
Highly Cited
2000
Highly Cited
2000
Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis.
The interaction of cells with the extracellular matrix regulates cell adhesion, motility, growth, survival and differentiation… 
Highly Cited
1996
Highly Cited
1996
Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family.
The selective production of monoclonal antibodies (mAbs) reacting with defined cell surface-expressed molecules is now readily… 
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