Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells.

@article{Patnaik2006ComplexNA,
  title={Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells.},
  author={Santosh Kumar Patnaik and Barry Potvin and Susanne Carlsson and David H. Sturm and Hakon Leffler and Pamela Stanley},
  journal={Glycobiology},
  year={2006},
  volume={16 4},
  pages={
          305-17
        }
}
Galectins are implicated in a large variety of biological functions, many of which depend on their carbohydrate-binding ability. Fifteen members of the family have been identified in vertebrates based on binding to galactose (Gal) that is mediated by one or two, evolutionarily conserved, carbohydrate-recognition domains (CRDs). Variations in glycan structures expressed on glycoconjugates at the cell surface may, therefore, affect galectin binding and functions. To identify roles for different… CONTINUE READING

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