LEUKOCYTE ADHESION DEFICIENCY

Known as: adhesion deficiencies leukocyte, adhesions deficiency leukocyte, leucocyte adhesion deficiency 
A rare autosomal recessive immunodeficiency disorder caused by deficiency of CD18 expression. It is characterized by defects in neutrophil adhesion… (More)
National Institutes of Health

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Review
2012
Review
2012
Leukocyte trafficking from the blood stream to tissues is essential for continuous surveillance of foreign antigens. This dynamic… (More)
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Review
2012
Review
2012
Leukocyte adhesion deficiency (LAD) is an immunodeficiency caused by defects in the adhesion of leukocytes (especially… (More)
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Highly Cited
2006
Highly Cited
2006
Single gene mutations in beta integrins can account for functional defects of individual cells of the hematopoietic system. In… (More)
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Review
2000
Review
2000
Leukocyte adhesion deficiency (LAD) type II is the second human disorder identified which involves the adhesion cascade. While in… (More)
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Highly Cited
1996
Highly Cited
1996
alpha(1,3)Fucosylated oligosaccharides represent components of leukocyte counterreceptors for E- and P-selectins and of L… (More)
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Highly Cited
1996
Highly Cited
1996
During the initial phase of the inflammatory response, leukocytes marginate and roll along the endothelial surface, a process… (More)
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Highly Cited
1992
Highly Cited
1992
Two point mutations were identified within the gene encoding bovine CD18 in a Holstein calf afflicted with leukocyte adhesion… (More)
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1992
1992
The clinical and autopsy findings in a patient with the severe form of leukocyte adhesion deficiency are presented. An 18-month… (More)
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Review
1988
Review
1988
Leukocyte adhesion deficiency disease is characterized by a mutation in the gene encoding the beta-subunit shared by three… (More)
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Highly Cited
1987
Highly Cited
1987
Leukocyte adhesion deficiency (LAD) is a recently recognized autosomal-recessive trait characterized by recurrent bacterial… (More)
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