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LCT gene

Known as: LACTASE-PHLORIZIN HYDROLASE, LACTASE, LCT 
National Institutes of Health

Related topics

Related topics

2 relations
Lactase-Phlorizin Hydrolasebeta-Galactosidase

Papers overview

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Highly Cited
2016
Highly Cited
2016
Lactase non-persistence is directed by DNA variation-dependent epigenetic aging
The inability to digest lactose, due to lactase nonpersistence, is a common trait in adult mammals, except in certain human… 
Highly Cited
2016
Highly Cited
2016
The quality of low lactose milk is affected by the side proteolytic activity of the lactase used in the production process.
Highly Cited
2014
Highly Cited
2014
Genetic origins of lactase persistence and the spread of pastoralism in Africa.
Highly Cited
2011
Highly Cited
2011
The −14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1α binding site and increases lactase promoter activity
In most people worldwide intestinal lactase expression declines in childhood. In many others, particularly in Europeans, lactase… 
Highly Cited
2010
Highly Cited
2010
A worldwide correlation of lactase persistence phenotype and genotypes
BackgroundThe ability of adult humans to digest the milk sugar lactose - lactase persistence - is a dominant Mendelian trait that… 
Highly Cited
2009
Highly Cited
2009
Lactase persistence-related genetic variant: population substructure and health outcomes
Lactase persistence is an autosomal-dominant trait that is common in European-derived populations. A basic tendency for lactase… 
Highly Cited
2008
Highly Cited
2008
Genetics of Lactase Persistence and Lactose Intolerance
■ Abstract The enzyme lactase that is located in the villus enterocytes of the small intestine is responsible for digestion of… 
Highly Cited
1994
Highly Cited
1994
The polymorphic expression of lactase in adults is regulated at the messenger RNA level.
Highly Cited
1990
Highly Cited
1990
COORDINATE EXPRESSION OF LACTASE-PHLORIZIN HYDROLASE (L-PH) mRNA AND ENZYME LEVELS IN RAT INTESTINE DURING DEVELOPMENT
The development of rat intestinal L-Ph specific activity displays a well-known post weaning decline. In contrast, total lactase… 
Highly Cited
1989
Highly Cited
1989
Control of lactase in human adult-type hypolactasia and in weaning rabbits and rats.
Lactase is an enterocyte brush-border membrane beta-glycosidase that splits lactose, the sugar of milk. In mammals, including… 
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