Skip to search formSkip to main contentSkip to account menu

LCAT gene

Known as: lecithin-cholesterol acyltransferase, LCAT, LECITHIN:CHOLESTEROL ACYLTRANSFERASE 
National Institutes of Health

Related topics

Related topics

2 relations
Phosphatidylcholine-Sterol O-Acyltransferasephosphatidylcholine-sterol O-acyltransferase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Mechanism and Physiologic Significance of the Suppression of Cholesterol Esterification in Human Interstitial Fluid
Cholesterol esterification in high density lipoproteins (HDLs) by lecithin:cholesterol acyltransferase (LCAT) promotes… 
2013
2013
21-Methylpyrenyl-cholesterol stably and specifically associates with lipoprotein peripheral hemi-membrane: a new labelling tool.
2012
2012
Impaired functionality of HDL in diabetes
Patients with type 2 diabetes mellitus (T2DM) remain at higher risk of cardiovascular diseases than nondiabetic subjects even… 
Review
2011
Review
2011
Lecithin-cholesterol acyltransferase (LCAT) deficiency without mutations in the coding sequence: a case report and literature review.
Familial lecithin-cholesterol acyltransferase (LCAT) deficiency (FLD) is a rare genetic disease characterized by corneal… 
2006
2006
Familial lecithin-cholesterol acyltransferase deficiency: biochemical characteristics and molecular analysis of a new LCAT mutation in a Polish family.
2002
2002
Identification of an IL-6 response element in the human LCAT promoter.
2001
2001
Alteration of plasma HDL cholesteryl ester composition with transgenic expression of a point mutation (E149A) of human LCAT.
We have previously identified a single amino acid mutation (hE149A) in human LCAT that increases its in vitro reactivity with… 
1997
1997
Amino Acid Residue 149 of Lecithin:Cholesterol Acyltransferase Determines Phospholipase A2 and Transacylase Fatty Acyl Specificity*
Human LCAT prefers phosphatidylcholine (PC) with sn-1-palmitoyl-2-oleoyl PC (POPC) as substrate for cholesteryl ester synthesis… 
1993
1993
Lecithin:cholesterol acyltransferase: role of N-linked glycosylation in enzyme function.
Lecithin:cholesterol acyltransferase (LCAT; phosphatidylcholine-sterol acyltransferase, EC 2.3.1.43) is a glycoprotein which is… 
1992
1992
Decreased lecithin: Cholesterol acyltransferase activity in the plasma of hypercholesterolemic pigs
Lecithincholesterol acyltransferase (LCAT) activity levels were determined, as function of plasma total cholesterol (TC) in 13… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)