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Phosphatidylcholine-Sterol O-Acyltransferase

Known as: Phosphatidylcholine Sterol O Acyltransferase, LCAT, Lecithin Acyltransferase 
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Intracellular lipid droplets (LDs) are found in a wide variety of cell types and have been recognized as organelles with unique… Expand
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Review
2017
Review
2017
Graphical abstract Heterogeneity, metabolism and biological activities of normal functional HDL (A) and of HDL with defective… Expand
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Highly Cited
2008
Highly Cited
2008
HDL protects against vascular disease by accepting free cholesterol from macrophage foam cells in the artery wall. This pathway… Expand
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Review
2006
Review
2006
Dietary sphingomyelin (SM) is hydrolyzed by intestinal alkaline sphingomyelinase and neutral ceramidase to sphingosine, which is… Expand
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Highly Cited
2005
Highly Cited
2005
The microencapsulation vesicle (MCV) method is a liposome preparation technique that reproducibly produces liposomes with… Expand
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Review
2005
Review
2005
Reverse cholesterol transport (RCT) is a pathway by which accumulated cholesterol is transported from the vessel wall to the… Expand
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Highly Cited
2004
Highly Cited
2004
In individuals with type 2 diabetes, metabolic syndrome, and the combined dyslipidemia, cardiovascular risk is increased by a… Expand
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Highly Cited
1999
Highly Cited
1999
Expression of human lecithin cholesterol acyltransferase (LCAT) in mice (LCAT-Tg) leads to increased high density lipoprotein… Expand
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Highly Cited
1988
Highly Cited
1988
The leaf membrane lipids of many plant species, including Arabidopsis thaliana (L.) Heynh., are synthesized by two complementary… Expand
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Highly Cited
1987
Highly Cited
1987
The transfer of insoluble cholesteryl esters among lipoprotein particles is a vital step in normal cholesterol homeostasis and… Expand
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