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Phosphatidylcholine-Sterol O-Acyltransferase

Known as: Phosphatidylcholine Sterol O Acyltransferase, LCAT, Lecithin Acyltransferase 
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Acyltransferase
In BloodLCAT geneLecithin cholesterol acyltransferase:CCnc:Pt:Ser/Plas:QnProcess of secretion
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Perilipins: a diversity of intracellular lipid droplet proteins
Intracellular lipid droplets (LDs) are found in a wide variety of cell types and have been recognized as organelles with unique… Expand
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Review
2017
Review
2017
Effects of curcumin on HDL functionality
Graphical abstract Heterogeneity, metabolism and biological activities of normal functional HDL (A) and of HDL with defective… Expand
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Highly Cited
2008
Highly Cited
2008
Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I
HDL protects against vascular disease by accepting free cholesterol from macrophage foam cells in the artery wall. This pathway… Expand
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Review
2006
Review
2006
Absorption and lipoprotein transport of sphingomyelin Published, JLR Papers in Press, October 26, 2005.
Dietary sphingomyelin (SM) is hydrolyzed by intestinal alkaline sphingomyelinase and neutral ceramidase to sphingosine, which is… Expand
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Highly Cited
2005
Highly Cited
2005
Encapsulation efficiency of water-soluble and insoluble drugs in liposomes prepared by the microencapsulation vesicle method.
The microencapsulation vesicle (MCV) method is a liposome preparation technique that reproducibly produces liposomes with… Expand
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Review
2005
Review
2005
Reverse cholesterol transport and cholesterol efflux in atherosclerosis.
Reverse cholesterol transport (RCT) is a pathway by which accumulated cholesterol is transported from the vessel wall to the… Expand
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Highly Cited
2004
Highly Cited
2004
Atherogenic index of plasma [log(triglycerides/HDL-cholesterol)]: theoretical and practical implications.
In individuals with type 2 diabetes, metabolic syndrome, and the combined dyslipidemia, cardiovascular risk is increased by a… Expand
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Highly Cited
1999
Highly Cited
1999
Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice.
Expression of human lecithin cholesterol acyltransferase (LCAT) in mice (LCAT-Tg) leads to increased high density lipoprotein… Expand
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Highly Cited
1988
Highly Cited
1988
Altered regulation of lipid biosynthesis in a mutant of Arabidopsis deficient in chloroplast glycerol-3-phosphate acyltransferase activity.
The leaf membrane lipids of many plant species, including Arabidopsis thaliana (L.) Heynh., are synthesized by two complementary… Expand
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Highly Cited
1987
Highly Cited
1987
Cloning and sequencing of human cholesteryl ester transfer protein cDNA
The transfer of insoluble cholesteryl esters among lipoprotein particles is a vital step in normal cholesterol homeostasis and… Expand
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