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Phosphatidylcholine-Sterol O-Acyltransferase

Known as: Phosphatidylcholine Sterol O Acyltransferase, LCAT, Lecithin Acyltransferase 
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Acyltransferase
In BloodLCAT geneLecithin cholesterol acyltransferase:CCnc:Pt:Ser/Plas:QnProcess of secretion

Papers overview

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Highly Cited
1998
Highly Cited
1998
The Hydrophobic Face Orientation of Apolipoprotein A-I Amphipathic Helix Domain 143–164 Regulates Lecithin:Cholesterol Acyltransferase Activation*
Apolipoprotein A-I (apoA-I) activates the plasma enzyme lecithin:cholesterol acyltransferase (LCAT), catalyzing the rapid… 
Review
1997
Review
1997
Reverse cholesterol transport--a review of the process and its clinical implications.
Highly Cited
1996
Highly Cited
1996
Sphingomyelin Inhibits the Lecithin-Cholesterol Acyltransferase Reaction with Reconstituted High Density Lipoproteins by Decreasing Enzyme Binding*
Lecithin-cholesterol acyltransferase (LCAT) catalyzes the formation of cholesterol esters on high density lipoproteins (HDL) and… 
Highly Cited
1982
Highly Cited
1982
Reaction of human lecithin cholesterol acyltransferase with synthetic micellar complexes of apolipoprotein A-I, phosphatidylcholine, and cholesterol.
Highly Cited
1982
Highly Cited
1982
Population-based reference values for lecithin-cholesterol acyltransferase (LCAT).
Highly Cited
1979
Highly Cited
1979
Effect of human plasma apolipoproteins on the activity of purified lecithin: cholesterol acyltransferase.
An active preparation of lecithin: cholesterol acyltransferase (LCAT, EC 2.3.1.43) was isolated from human plasma by density… 
Highly Cited
1975
Highly Cited
1975
Chemically induced lipid phase separation in model membranes containing charged lipids: a spin label study.
Highly Cited
1972
Highly Cited
1972
Isolation and characterization of lymphocyte plasma membranes.
Highly Cited
1972
Highly Cited
1972
Biochemical Development of Surface Activity in Mammalian Lung. IV. Pulmonary Lecithin Synthesis in the Human Fetus and Newborn and Etiology of the Respiratory Distress Syndrome
Extract: The surface-active complex lining alveoli in normal lung lowers surface tension on expiration, thus preventing alveolar… 
Highly Cited
1967
Highly Cited
1967
Studies in the biosynthesis of hepatic and biliary lecithins.
Male rats with biliary cannulae were injected with linoleate-1-(14)C, stearate-1-(14)C, palmitate-9-10-(3)H, phosphate-(32)P, l… 
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