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Effect of Lactobacillus plantarum 299v on cardiovascular disease risk factors in smokers.
L. plantarum administration leads to a reduction in cardiovascular disease risk factors and could be useful as a protective agent in the primary prevention of atherosclerosis in smokers. Expand
Combination therapy of statin with flavonoids rich extract from chokeberry fruits enhanced reduction in cardiovascular risk markers in patients after myocardial infraction (MI).
Ch chokeberry flavonoids reduce the severity of inflammation, regardless of statins, and can be used clinically for secondary prevention of ischaemic heart disease. Expand
Rapid quantification of human ABCA1 mRNA in various cell types and tissues by real-time reverse transcription-PCR.
A rapid, sensitive, specific, and reproducible real-time reverse transcription-PCR method for detection and quantification of ABCA1 transcripts in total RNA isolated from cultured human cells and tissues is developed. Expand
Chronic intake of potato chips in humans increases the production of reactive oxygen radicals by leukocytes and increases plasma C-reactive protein: a pilot study.
It is shown that chronic ingestion of acrylamide-containing products induces a proinflammatory state, a risk factor for progression of atherosclerosis, and it has been shown also that acrieslamide increases the production of reactive oxygen species in isolated human monocyte-macrophages in vitro and decreases the cellular glutathione concentration. Expand
Simvastatin inhibits the oxidation of low-density lipoproteins by activated human monocyte-derived macrophages.
Human monocyte-derived macrophages treated with increasing concentrations of the HMG-CoA reductase inhibitor, simvastatin, showed a dose-dependent decrease in superoxide formation in response to activation by phorbol myristate acetate, indicating that simVastatin might prevent atherosclerosis by additional mechanisms besides its hypocholesterolemic activity. Expand
Stabilisation of atherosclerotic plaques. Position paper of the European Society of Cardiology (ESC) Working Group on atherosclerosis and vascular biology.
There is a strong biological basis and supportive clinical evidence that low-density lipoprotein lowering with statins is useful for the stabilisation of vulnerable plaques and some clinical evidence for the usefulness of antiplatelet agents, beta blockers and renin-angiotensin-aldosterone system inhibitors for plaque stabilisation. Expand
Extracts from Epilobium sp. herbs induce apoptosis in human hormone‐dependent prostate cancer cells by activating the mitochondrial pathway
The aim of this work was to determine the effect of standardized aqueous extracts from Epilobium angustifolium L., E. parviflorum Schreb. and E. hirsutum L. herbs on the apoptosis ofExpand
Propionate reduces the cytokine-induced VCAM-1 and ICAM-1 expression by inhibiting nuclear factor-kappa B (NF-kappaB) activation.
Propionate may have antiinflammatory and possibly antiatherogenic properties and warrant further investigation into the therapeutic effects of propionate on a number of pathological events nvolving leukocyte recruitment. Expand
Protective properties of artichoke (Cynara scolymus) against oxidative stress induced in cultured endothelial cells and monocytes.
It is demonstrated that artichoke extracts have marked protective properties against oxidative stress induced by inflammatory mediators and ox-LDL in cultured endothelial cells and monocytes. Expand
Extracts from Epilobium sp. Herbs, Their Components and Gut Microbiota Metabolites of Epilobium Ellagitannins, Urolithins, Inhibit Hormone‐Dependent Prostate Cancer Cells‐(LNCaP) Proliferation and
Results of the work offer an explanation of the activity of Epilobium extracts and support the use of EpILobium preparations in the treatment of prostate diseases. Expand