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LC-1 compound

Known as: 13-(N,N-dimethyl)amino-4,5-epoxy-4,10-dimethyl-6-hydroxy-12-oic acid gamma-lactone-germacra-1(10)-ene, DMAPT cpd, dimethylamino-parthenolide 
National Institutes of Health

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1 relation

Broader (1)

Sesquiterpenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolide
Despite advances in prostate cancer therapy, dissemination and growth of metastases results in shortened survival. Here we… 
2017
2017
Abstract 4047: NF-kB inhibitor DMAPT enhances cisplatin efficacy and reduces its toxicity in a carcinogen-induced model of muscle-invasive bladder cancer
BACKGROUND: Nuclear factor kappaB (NF-κB) blocks apoptosis and promotes chemoresistance to drugs like cisplatin (CDDP). However… 
2017
2017
Abstract 1161: Dimethylaminoparthenolide (DMAPT), an oral nuclear factor kappa B inhibitor (NFκB), enhances radiation therapy and enhances epidermal growth factor tyrosine kinase inhibitor (EGFR TKI…
Introduction: NFκB can promote cancer and resistance to therapy as well as mediate tissue injury in response to radiation (XRT… 
2015
2015
Antitumor effect of antibody against a novel antigen (UOEH-LC-1) on lung cancer xenotransplanted into SCID mice: P2-141
Antitumor effect of antibody against a novel antigen (UOEH-LC-1) on lung cancer xenotransplanted into SCID mice Mizukami, Makiko… 
2013
2013
Efficacy of Dimethylaminoparthenolide and Sulindac in Combination With Gemcitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer
Objectives Pancreatic cancer remains one of the deadliest diseases, with limited surgical and treatment options. Two targets of… 
2011
2011
Inhibition of NF-κB and DNA double-strand break repair by DMAPT sensitizes non-small-cell lung cancers to X-rays.
1991
1991
The radioimmunolocalization of McAb LC-1 and its fragment in nude mice bearing lung adenocacinoma
1991
1991
Antitumor effect of McAb LC-1 and trichosanthin conjugation
1991
1991
A McAb LC-1 which against human lung cancer
1987
1987
28a-LC-1 ポリチオフェンの電気化学的ドーピングによる発光のクェンチング(分子性結晶・液晶・有機半導体)
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