LC-1 compound

Known as: 13-(N,N-dimethyl)amino-4,5-epoxy-4,10-dimethyl-6-hydroxy-12-oic acid gamma-lactone-germacra-1(10)-ene, DMAPT cpd, dimethylamino-parthenolide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2017
02420112017

Papers overview

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2017
2017
Dimethylaminoparthenolide (DMAPT), a water-soluble analogue of natural product parthenolide, possesses anti-inflammatory and anti… (More)
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2017
2017
Constitutive activation of the pro-survival transcription factor NF-κB has been associated with resistance to both chemotherapy… (More)
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2017
2017
Breast cancer progression is associated with systemic effects, including functional limitations and sarcopenia without the… (More)
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2017
2017
Despite optimal chemotherapy, radiotherapy (RT), and/or surgery, non-small-cell lung carcinoma (NSCLC) remains the leading cause… (More)
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2016
2016
Triple-negative breast cancers (TNBCs) are aggressive forms of breast carcinoma associated with a high rate of recidivism. In… (More)
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2015
2015
The transcription factor nuclear factor-kappaB (NF-κB) is constitutively active in several cancers and is a target of therapeutic… (More)
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2015
2015
Advances in anticancer chemotherapy have been hindered by the lack of biocompatibility of new prospective drugs. One significant… (More)
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2013
2013
OBJECTIVES Pancreatic cancer remains one of the deadliest diseases, with limited surgical and treatment options. Two targets of… (More)
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2011
2011
Dimethylaminoparthenolide (DMAPT) is a water soluble parthenolide analog with preclinical activity in hematologic malignancies… (More)
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2011
2011
We investigated the efficacy and mechanism of dimethylaminoparthenolide (DMAPT), an NF-κB inhibitor, to sensitize human lung… (More)
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