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Radiation-Induced Bystander Effects: What Are They, and How Relevant Are They to Human Radiation Exposures?
The term radiation-induced bystander effect is used to describe radiation-induced biological changes that manifest in unirradiated cells remaining within an irradiated cell population. Despite theirExpand
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The Linear No-Threshold Model does not Hold for Low-Dose Ionizing Radiation
Abstract Hooker, A. M., Bhat, M., Day, T. K., Lane, J. M., Swinburne, S. J., Morley, A. A. and Sykes, P. J. The Linear No-Threshold Model does not Hold for Low-Dose Ionizing Radiation. Radiat. Res.Expand
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Quantitation of targets for PCR by use of limiting dilution.
We describe a general method to quantitate the total number of initial targets present in a sample using limiting dilution, PCR and Poisson statistics. The DNA target for the PCR was the rearrangedExpand
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Extremely Low Priming Doses of X Radiation Induce an Adaptive Response for Chromosomal Inversions in pKZ1 Mouse Prostate
Abstract Day, T. K., Zeng, G., Hooker, A. M., Bhat, M., Scott, B. R., Turner, D. R. and Sykes, P. J. Extremely Low Priming Doses of X Radiation Induce an Adaptive Response for Chromosomal InversionsExpand
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Elevated levels of versican but not decorin predict disease progression in early-stage prostate cancer.
Patients with clinically localized prostate cancer who might be cured by aggressive management are not easily identified using current clinical information. Additional, more accurate, biomarkers ofExpand
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Adaptive Response for Chromosomal Inversions in pKZ1 Mouse Prostate Induced by Low Doses of X Radiation Delivered after a High Dose
Abstract Day, T. K., Zeng, G., Hooker, A. M., Bhat, M., Scott, B. R., Turner, D. R. and Sykes, P. J. Adaptive Response for Chromosomal Inversions in pKZ1 Mouse Prostate Induced by Low Doses of XExpand
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Morbidity in the forearm flap donor arm
Abstract A restrospective study was carried out of the morbidity in the donor limb following use of the radial forearm flap in 27 patients. Of the 13 patients whose flaps contained bone, 4 sustainedExpand
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Non-linear chromosomal inversion response in prostate after low dose X-radiation exposure.
Somatic intrachromosomal recombination can result in inversions and deletions in DNA, which are important mutations in cancer. The pKZ1 chromosomal inversion assay is a sensitive assay for studyingExpand
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In Vivo Mutagenic Effect of Very Low Dose Radiation
Almost all of our knowledge about the mutational effect of radiation has come from high dose studies which are generally not relevant to public exposure. The pKZ1 mouse recombination mutagenesisExpand
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The PKZ1 Recombination Mutation Assay: A Sensitive Assay for Low Dose Studies
The majority of mutation studies are performed at high doses of DNA damaging agents due to the insensitivity of most mutation assays. Extrapolation using a linear no-threshold (LNT) dose responseExpand
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