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LAT gene

Known as: LINKER FOR ACTIVATION OF T CELLS, LAT1, linker for activation of T cells, transmembrane adaptor 
 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Lipid microdomains are postulated to regulate many membrane-associated processes but have remained highly controversial. Here we… Expand
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Highly Cited
2010
Highly Cited
2010
The organization and dynamics of receptors and other molecules in the plasma membrane are not well understood. Here we analyzed… Expand
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Highly Cited
2010
Highly Cited
2010
The physical basis for protein partitioning into lipid rafts remains an outstanding question in membrane biology that has… Expand
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Highly Cited
2008
Highly Cited
2008
Mutant mice where tyrosine 136 of linker for activation of T cells (LAT) was replaced with a phenylalanine (LatY136F mice… Expand
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Highly Cited
2008
Highly Cited
2008
Nutrient transporters and ABC efflux pumps at the blood-brain barrier are major determinants of drug penetration into the brain… Expand
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Highly Cited
2005
Highly Cited
2005
System L amino acid transporters mediate the movement of bulky neutral amino acids across cell membranes. Until now three… Expand
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Highly Cited
2003
Highly Cited
2003
The adaptor molecule, linker for activation of T cells (LAT), is essential in T cell activation and development; a similar… Expand
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Highly Cited
2002
Highly Cited
2002
FcεRI activation of mast cells is thought to involve Lyn and Syk kinases proximal to the receptor and the signaling complex… Expand
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Highly Cited
2001
Highly Cited
2001
Polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (20:5 (n-3)) inhibit T lymphocyte activation probably by… Expand
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Highly Cited
1998
Highly Cited
1998
A cDNA was isolated from rat C6 glioma cells by expression cloning which encodes a novel Na+-independent neutral amino acid… Expand
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