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Negative Regulation of Mast Cell Signaling and Function by the Adaptor LAB/NTAL
Engagement of the Fcɛ receptor I (FcɛRI) on mast cells and basophils initiates signaling pathways leading to degranulation. Early activation events include tyrosine phosphorylation of twoExpand
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Molecular phylogenetic characterization of Collyriclum faba with reference to its three host-specific ecotypes.
Collyriclum faba (Bremser in Schmalz, 1831) is a monostome digenetic trematode with unknown life cycle. On its definitive bird host, C. faba occurs in pairs within a subcutaneous cyst, the locationExpand
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Red List of Czech spiders: 3rd edition, adjusted according to evidence-based national conservation priorities
Abstract The knowledge on spiders of the Czech Republic has substantially improved since the second version of the national Red List was published, mainly due to large-scale field records and theExpand
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Regulation of cys-based protein tyrosine phosphatases via reactive oxygen and nitrogen species in mast cells and basophils.
Activation of mast cells and basophils is accompanied by the production of reactive oxygen and nitrogen species that regulate diverse signaling pathways leading to the release of inflammatoryExpand
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Involvement of filamentous actin in setting the threshold for degranulation in mast cells
Previous studies using cytochalasins and latrunculin B, inhibitors of actin polymerization, showed that filamentous (F)‐actin had a negative regulatory role in Fcϵ receptor I (FcϵRI) signaling. HowExpand
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Molecular and comparative morphological analysis of central European parasitic flatworms of the superfamily Brachylaimoidea Allison, 1943 (Trematoda: Plagiorchiida) - CORRIGENDUM.
The authors apologise for errors that appear in the molecular phylogenetic analyses of the ND1 locus. The ND1 sequences of Brachylaima mesostoma, NCBI Acc. Nos. KT074969 and KT074970, wereExpand
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Soil penetrability as a key factor affecting the nesting of burrowing birds
  • P. Heneberg
  • Environmental Science
  • Ecological Research
  • 1 March 2009
Soil penetrability resistance was found to be crucial for nest site selection of all three Central European burrowing bird species—Sand Martins (Riparia riparia), European Bee-eaters (MeropsExpand
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Designing a broad-spectrum integrative approach for cancer prevention and treatment.
Targeted therapies and the consequent adoption of "personalized" oncology have achieved notable successes in some cancers; however, significant problems remain with this approach. Many targetedExpand
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Cancer prevention and therapy through the modulation of the tumor microenvironment.
Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve dynamically through indirectExpand
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Migrastatics—Anti-metastatic and Anti-invasion Drugs: Promises and Challenges
In solid cancers, invasion and metastasis account for more than 90% of mortality. However, in the current armory of anticancer therapies, a specific category of anti-invasion and antimetastatic drugsExpand
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