LAF4 protein, human

Known as: LAF4, AFF3 protein, human, Lymphoid Nuclear Protein Related to AF4 
AF4/FMR2 family member 3 (1226 aa, ~133 kDa) is encoded by the human AFF3 gene. This protein is involved in the regulation of both development and… (More)

Topic mentions per year

Topic mentions per year

1983-2014
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Papers overview

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2014
2014
Patients with chronic obstructive pulmonary disease (COPD) who are defined as frequent exacerbators suffer with 2 or more… (More)
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2008
2008
The AML1 gene is frequently rearranged by chromosomal translocations in acute leukemia. We identified that the LAF4 gene on 2q11… (More)
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Highly Cited
2007
Highly Cited
2007
Chimeric proteins joining the histone methyltransferase MLL with various fusion partners trigger distinctive lymphoid and myeloid… (More)
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2003
2003
We showed that the LAF4 gene on 2q11.2–12 was fused to the MLL gene on 11q23 in a pediatric patient with CD10 positive acute… (More)
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2002
2002
Infant acute lymphoblastic leukemia (ALL) with MLL gene rearrangements is characterized by a proB phenotype and a poor clinical… (More)
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2002
2002
The cerebral cortex is a tissue with a high degree of neuronal diversity. It consists of six cell layers with a unique set of… (More)
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2001
2001
AbstractExpansion of the FRAXE CCG repeat to a full mutation is associated with methylation and transcriptional silencing of the… (More)
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2001
2001
The (11;19)(q23;p13.1) translocation in acute leukemia leads to the generation of a chimeric protein that fuses MLL to the… (More)
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1999
1999
Infant acute lymphoblastic leukemia (ALL) with MLL gene rearrangements is characterized by early pre-B phenotype (CD10(-)/CD19… (More)
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Review
1996
Review
1996
Laf4 coding sequence subcloned into the EcoRI site of pBluescript vector SK(Stratagene) [1]. Laf4-1inked loci, Dst and l l lr l… (More)
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