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AFF3 gene

Known as: AFF3, AF4/FMR2 family member 3, AF4/FMR2 FAMILY, MEMBER 3 
This gene is involved in transcriptional activation and is purported to play roles in lymphoid development and oncogenesis.
National Institutes of Health

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AFF3 wt Allele
Homo sapiensLAF4 protein, humanTranscriptional ActivationTranscriptional Regulation

Papers overview

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2018
2018
P28 Identification of a shear stress responsive novel gene in the intron of laf4
A novel gene was recently discovered using microarray gene profiling of shear stress–induced genes in mouse embryonic stem cells… 
2017
2017
Genetics of Diabetic Kidney Disease-From the Worst of Nightmares to the Light of Dawn?
Despite improved clinical care in patients with diabetes, diabetic complications remain a major healthcare burden. The management… 
2014
2014
ИССЛЕДОВАНИЕ СТРУКТУРЫ ХИМЕРНЫХ ГЕНОВ С УЧАСТИЕМ ГЕНА MLL ПРИ ОСТРЫХ ЛЕЙКОЗАХ У ДЕТЕЙ ПЕРВОГО ГОДА ЖИЗНИ
Р е з ю м е. Целью данной работы являлось описание механизмов образования химерных генов с вовлечением гена MLL… 
2014
2014
THU0458 Analysis of Genetic Factors Associated with Progression of Functional Disability in Japanese Patients with Rheumatoid Arthritis
Background Rheumatoid arthritis (RA) is characterized by chronic inflammation and joint destruction, resulting in deteriorated… 
2013
2013
Independent replication analysis of genetic loci with previous evidence of association with juvenile idiopathic arthritis
BackgroundOver the last five years, there have been numerous reports of association of juvenile idiopathic arthritis with single… 
2013
2013
Chromosome 2 q 31 . 1 Associates with ESRD in Women with Type 1 Diabetes
Sex and genetic variation influence the risk of developing diabetic nephropathy and ESRD in patients with type 1 diabetes. We… 
2013
2013
AFF3, une nouvelle cible de la voie Wnt/b-catenin impliquée dans la tumorigenèse cortico-surrénalienne
2013
2013
OP0209 Genetic variance in IL2RA associates with progression of joint destruction and circulating SIL-2RA levels in rheumatoid arthritis
Background Since most therapeutic strategies are targeted to affect pathways of disease progression, interrogation of the genome… 
2011
2011
Copy number variation in common disease.
The search for genetic variants that confer an increased risk for the development of common diseases such as Graves’ disease (GD… 
2008
2008
A novel fusion 5′AFF3/3′BCL2 originated from a t(2;18)(q11.2;q21.33) translocation in follicular lymphoma
Follicular lymphoma is the second most frequent type of non-Hodgkin's lymphoma in adults. The basic molecular defect consists of… 
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