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LA 419

Known as: LA-419, LA419 cpd 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Isosorbide Dinitrate
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Treatment with LA-419 prevents monocrotaline-induced pulmonary hypertension and lung injury in the rat.
We evaluated the therapeutic potential of LA-419, a hybrid organic nitrate that donates nitric oxide and thiol groups, to improve… 
Review
2010
Review
2010
Nitric oxide pathway in hypertrophied heart: new therapeutic uses of nitric oxide donors
Left ventricular hypertrophy (LVH) is regarded as a complication common to a number of cardiovascular diseases, including… 
Review
2009
Review
2009
LA-419, a nitric-oxide donor for the treatment of cardiovascular disorders.
LA-419, currently being developed by Lacer SA, is a thiol-containing analog of isosorbide mononitrate that is undergoing… 
2008
2008
The Nitric Oxide Donor LA-419 [S-(6-Nitro-oxi-hexahydro-furo[3,2-b]furan-3-1-il)thioacetate] Prevents Intestinal Dysmotility, Bacterial Translocation, and Inflammation in a Rat Model of Enteritis
Indomethacin induces a chronic model of inflammatory bowel disease (IBD) characterized by spontaneous relapses of inflammation… 
2008
2008
Estudio del efecto cardíaco de un nuevo donador de óxido nítrico en un modelo experimental de cardiopatía hipertensiva
En los desordenes cardiovasculares como la hipertrofia y la insuficiencia cardiaca existe una produccion reducida de oxido… 
2006
2006
Gateways to clinical trials.
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data the… 
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