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Isosorbide Dinitrate

Known as: Dinitrate, Isosorbide, 1,4:3,6-Dianhydrosorbitol 2,5-dinitrate, Dinitrate d'isosorbide 
The dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide dinitrate relaxes vascular smooth muscle by formation… 
National Institutes of Health

Related topics

Related topics

41 relations
Angina PectorisCongestive heart failureCoronary heart diseaseCraniocerebral Trauma

Narrower (16)

Cardonit 40CarvasinIsochronIsoket

Broader (2)

Sugar AlcoholsVasodilator Agents

Papers overview

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Highly Cited
2000
Highly Cited
2000
Hypertonic saline-dextran improves intestinal perfusion and survival in porcine endotoxin shock
ObjectiveTo examine the effects of hypertonic (7.5%) saline-6% dextran 70 (HSD) and isotonic (0.9%) saline-6% dextran 70 (ISD) on… 
Highly Cited
1996
Highly Cited
1996
Mild systolic dysfunction in heart failure (left ventricular ejection fraction >35%): baseline characteristics, prognosis and response to therapy in the Vasodilator in Heart Failure Trials (V-HeFT)
Highly Cited
1991
Highly Cited
1991
TRAFFIC MODELS FOR ISDN DATA USERS: OFFICE AUTOMATION APPLICATION
Prior to the introduction of the Integrated Services Digital Network (ISDN), traffic engineering for this new technology required… 
Review
1991
Review
1991
Developing a cohesive traffic management strategy for ATM networks
The background and some of the rationale for the development of an asynchronous transfer mode (ATM) traffic management framework… 
Highly Cited
1989
Highly Cited
1989
Comparison of relaxation induced by glyceryl trinitrate, isosorbide dinitrate, and sodium nitroprusside in bovine airways.
Nitrates are generally regarded as bronchial smooth muscle relaxants. However, reports about the clinical efficacy of the… 
Highly Cited
1988
Highly Cited
1988
Sequential neurohumoral measurements in patients with congestive heart failure.
Highly Cited
1981
Highly Cited
1981
Kinetics of isosorbide dinitrate and relationships to pharmacological effects.
1 The inter-relationships among oral isosorbide dinitrate (ISDN) dose, drug pharmacokinetics and pharmacological effects were… 
Highly Cited
1980
Highly Cited
1980
Oral Isosorbide Dinitrate in the Treatment of Angina Pectoris: Dose‐Response Relationship and Duration of Action During Acute Therapy
The duration of effects of single oral doses of 15, 30 and 60 mg of isosorbide dinitrate (ISDN) were studied in 12 patients with… 
Highly Cited
1979
Highly Cited
1979
Nifedipine therapy for refractory coronary arterial spasm.
Highly Cited
1973
Highly Cited
1973
GLC determination of nitroglycerin and isosorbide dinitrate in human plasma.
A procedure is described for the identification and quantitative determination of nitroglycerin and isosorbide dinitrate in… 
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