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L 695256

Known as: L 695,256, L-695,256, L-695256 
National Institutes of Health

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2 relations

Broader (2)

CarbapenemsImidazoles

Papers overview

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Highly Cited
2004
Highly Cited
2004
PBP 2a Mutations Producing Very-High-Level Resistance to Beta-Lactams
ABSTRACT Resistance to the beta-lactam class of antibiotics in methicillin-resistant Staphylococcus aureus (MRSA) is mediated by… 
1996
1996
Species specificity of 2-aryl carbapenem-induced immune-mediated hemolytic anemia in primates.
1996
1996
Pharmacokinetics in nonhuman primates of a prototype carbapenem active against methicillin-resistant Staphylococcus aureus
Pharmacokinetic parameters were determined for imipenem-cilastatin and a carbapenem antibiotic, L-695,256, active against… 
1995
1995
In vitro and in vivo antistaphylococcal activities of L-695,256, a carbapenem with high affinity for the penicillin-binding protein PBP 2a
L-695,256 is a synthetic carbapenem beta-lactam antibiotic that binds with a high degree of affinity to penicillin-binding… 
1995
1995
Comparative in vitro activities of L-695,256, a novel carbapenem, against gram-positive bacteria
The in vitro activity of a prototype 2-aryl carbapenem, L-695,256, against gram-positive bacteria was examined. All streptococci… 
1995
1995
Comparative antibacterial activity of L-695,256, a carbapenem active against methicillin-resistant staphylococci
The activity of a new prototype carbapenem, L-695,256, against clinical isolates of gram-positive and gram-negative aerobes was… 
1995
1995
High-yield expression, refolding, and purification of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus strain 27R.
The mecA-27R gene, which encodes PBP2a from methicillin-resistant Staphylococcus aureus strain 27R, was modified to remove the… 
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