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L 659989

Known as: L-659,989 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Furans

Papers overview

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1996
1996
Mechanism of ATP-induced leukocyte adherence to cultured pulmonary artery endothelial cells.
Previously we have shown that ATP enhances the adherence of HL-60 cells and human neutrophils to bovine pulmonary artery… 
1995
1995
Susceptibility to platelet-activating factor-induced airway hyperreactivity and hyperpermeability: interstrain variation and genetic control.
Platelet-activating factor (PAF) is a proinflammatory mediator known to elicit changes in airway reactivity and vascular… 
1994
1994
Protective Effects of L‐659,989, a Platelet‐Activating Factor Receptor Antagonist, in Myocardial Ischemia and Reperfusion in Rats
Summary The cardioprotective effects of L-659,989, a specific platelet-activating factor (PAF) receptor antagonist, were… 
1992
1992
Platelet activating factor interaction with tumor necrosis factor and myocardial depressant factor in splanchnic artery occlusion shock.
1992
1992
Bacterial lipopolysaccharide up-regulates platelet-activating factor-stimulated Ca2+ mobilization and eicosanoid release in human Mono Mac 6 cells.
When human monocytic Mono Mac 6 cells were treated with bacterial LPS (10 ng/ml, 72 h), they showed an increase in phagocytic… 
1991
1991
Resistance and exchange microvessels are modulated by different PAF receptors.
Using several platelet activating factor (PAF) receptor antagonists, we investigated whether a differential receptor sensitivity… 
1991
1991
Prolongation of parturition in the pregnant rat following treatment with a platelet activating factor receptor antagonist.
The presence of platelet activating factor (PAF) in amniotic fluid of women only in labor is indicative of a role for PAF in… 
1990
1990
Platelet-activating factor is a renal vasodilator in the anesthetized rat.
In view of the potent vasoactive properties of platelet-activating factor (PAF), we investigated the renal hemodynamic effects of… 
1989
1989
Antagonism of Paf‐induced oedema formation in rabbit skin: a comparison of different antagonists
1 Eight platelet activating factor (Paf) antagonists were evaluated as inhibitors of oedema formation in rabbit skin induced by… 
Highly Cited
1988
Highly Cited
1988
(+/-)-trans-2-(3-Methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5- trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonist.
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