Modified in vivo behavior of liposomes containing synthetic glycolipids.
- M. Wu, J. C. Robbins, R. Bugianesi, M. Ponpipom, T. Shen
- Biology, ChemistryBiochimica et Biophysica Acta
- 17 April 1981
Inhibition of stromelysin-1 (MMP-3) by P1'-biphenylylethyl carboxyalkyl dipeptides.
- C. Esser, R. Bugianesi, W. Hagmann
- Biology, ChemistryJournal of Medicinal Chemistry
- 14 March 1997
Inhibitors that contained halogenated biphenylylethyl residues at P1' proved to be superior in terms of enzyme potency and oral activity with 2(R)-[2-(4'-fluoro-4-biphenylyl)ethyl]-4(S)-n- butyl-1,5-pentane dioic acid 1-(alpha(S-tert-butylglycine methylamide) amide.
Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents.
- T. Biftu, D. Feng, M. Wyvratt
- Chemistry, BiologyBioorganic & Medicinal Chemistry Letters
- 1 July 2005
Purification and characterization of recombinant human farnesyl diphosphate synthase expressed in Escherichia coli.
- V. D. Ding, B. T. Sheares, J. Bergstrom, M. Ponpipom, L. Perez, C. Poulter
- Biology, ChemistryBiochemical Journal
- 1 April 1991
The results suggest that the structure and catalytic properties of the expressed FPP synthase fusion protein are virtually identical with those of the native human liver enzyme.
Synthesis of azide and amide analogs of platelet-activating factor and related derivatives
- M. Ponpipom, R. Bugianesi
- Chemistry, Biology
- 1 May 1984
Cell-specific ligands for selective drug delivery to tissues and organs.
- M. Ponpipom, R. Bugianesi, J. C. Robbins, T. Doebber, T. Shen
- Biology, ChemistryJournal of Medicinal Chemistry
- 1 December 1981
Various numbers of D-mannose residues have been attached via spacer arms to lysine, dilysine, and oligolysine backbones and the saccharide specificity of the macrophage receptor was demonstrated by the inactivity of the corresponding D-galactosyl peptide analogues.
Biochemical and pharmacological characterization of L-659,989: an extremely potent, selective and competitive receptor antagonist of platelet-activating factor.
- S. Hwang, M. Lam, A. Alberts, R. Bugianesi, J. C. Chabala, M. Ponpipom
- Biology, ChemistryJournal of Pharmacology and Experimental…
- 1 August 1988
In both [3H]PAF binding and PAF-induced platelet aggregation inhibition, L-659,989 was found to be a competitive inhibitor with an equilibrium dissociation constant (KB) of 1.5 and 1.7 nM, respectively, in rabbit platelets.
(+/-)-trans-2-(3-Methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5- trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonist.
- M. Ponpipom, S. Hwang, N. L. Gamble
- Biology, ChemistryBiochemical and Biophysical Research…
- 15 February 1988
Enhanced macrophage uptake of synthetically glycosylated human placental beta-glucocerebrosidase.
- T. Doebber, M. Wu, T. Shen
- Biology, ChemistryJournal of Biological Chemistry
- 10 March 1982
Cell surface carbohydrates for targeting studies
- M. Ponpipom, R. Bugianesi, T. Shen
- Chemistry, Biology
- 1 February 1980
These 6-(5-cholesten-3β-yloxy)hexyl 1-thioglycopyranosides have been incorporated into phospholipid vesicles for invivo tissue distribution studies.
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