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L 655,708

Known as: L-655708, L-655,708, L655708 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Imidazoles

Papers overview

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2020
2020
Mechanisms associated with the antidepressant-like effects of L-655,708
Previous research has demonstrated that selective modulation of hippocampal transmission by systemic administration of an α5… 
2019
2019
L-655,708 Does not Prevent Isoflurane-induced Memory Deficits in Old Mice
Abstract Background General anesthesia and increasing age are two main risk factors for postoperative cognitive dysfunction (POCD… 
2018
2018
Effects of L-655,708 on expression changes of GABA, glutamate, and beta-endorphin induced by propofol anesthesia in rats
Anesthetics are considered to be one of the important inducing factors of postoperative cognitive dysfunction (POCD). The… 
2017
2017
Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors
2014
2014
Effects of an &agr;5GABAA inverse agonist on MK-801-induced learning deficits in an incremental repeated acquisition task
N-methyl-D-aspartate receptors (NMDARs) are essential for several kinds of synaptic plasticity and play a critical role in… 
2011
2011
Neurosteroid modulation of benzodiazepine-sensitive GABAA tonic inhibition in supraoptic magnocellular neurons.
Interactions between neurosteroids and GABA receptors have attracted particular attention in the supraoptic nucleus (SON… 
2006
2006
GABAA receptor regulation of voluntary ethanol drinking requires PKCϵ
Protein kinase C (PKC) regulates a variety of neural functions, including ion channel activity, neurotransmitter release… 
2005
2005
In vivo labelling of alpha5 subunit-containing GABA(A) receptors using the selective radioligand [(3)H]L-655,708.
L-655,708 is an imidazobenzodiazepine possessing 30-70-fold selectivity for the benzodiazepine binding site of GABA(A) receptors… 
2005
2005
Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys.
Ethanol's ability to enhance GABA neurotransmission via GABA(A) receptors has been implicated as an important mechanism… 
2004
2004
Behavioral profile of L-655,708, a selective ligand for the benzodiazepine site of GABA-A receptors which contain the α5 subunit, in social encounters between male mice
GABA-A receptor is a transmembrane hetero-oligomeric protein which consists of five subunits, the combination of which confers… 
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