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L 655,708

Known as: L-655708, L-655,708, L655708 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Imidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Mechanisms associated with the antidepressant-like effects of L-655,708
Previous research has demonstrated that selective modulation of hippocampal transmission by systemic administration of an α5… 
2017
2017
Role of α4-containing GABAA receptors in limiting synaptic plasticity and spatial learning of female mice during the pubertal period
2017
2017
Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors
2011
2011
Tonic inhibition in spinal ventral horn interneurons mediated by α5 subunit-containing GABA(A) receptors.
2011
2011
Neurosteroid modulation of benzodiazepine-sensitive GABAA tonic inhibition in supraoptic magnocellular neurons.
Interactions between neurosteroids and GABA receptors have attracted particular attention in the supraoptic nucleus (SON… 
2006
2006
RAT PHARMACOKINETICS AND PHARMACODYNAMICS OF A SUSTAINED RELEASE FORMULATION OF THE GABAA α5-SELECTIVE COMPOUND L-655,708
The pharmacokinetic and pharmacodynamic (i.e., receptor occupancy) properties of L-655,708, a compound with selectivity for α5… 
2006
2006
GABAA receptor regulation of voluntary ethanol drinking requires PKCϵ
Protein kinase C (PKC) regulates a variety of neural functions, including ion channel activity, neurotransmitter release… 
2004
2004
Behavioral profile of L-655,708, a selective ligand for the benzodiazepine site of GABA-A receptors which contain the α5 subunit, in social encounters between male mice
GABA-A receptor is a transmembrane hetero-oligomeric protein which consists of five subunits, the combination of which confers… 
2002
2002
Anxiogenic-like activity of L-655,708, a selective ligand for the benzodiazepine site of GABAA receptors which contain the alpha-5 subunit, in the elevated plus-maze test
2001
2001
Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor.
L-655,708 is a ligand for the benzodiazepine site of the gamma-aminobutyric acid type A (GABA(A)) receptor that exhibits a 100… 
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