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L 652731

Known as: L-652,731 
National Institutes of Health

Papers overview

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Highly Cited
1991
Highly Cited
1991
Stimulation of neutrophil adherence to vascular endothelial cells by histamine and thrombin and its inhibition by PAF antagonists and dexamethasone
1 In order to clarify the roles of platelet‐activating factor (PAF) in histamine‐ and thrombin‐induced neutrophil adhesion to… 
1989
1989
Occurrence of platelet‐activating factor (PAF) in normal rat stomach and alteration of PAF level by water immersion stress
We detected platelet‐activating substance in gastrointestinal areas, which was confirmed to be platelet‐activating factor (PAF… 
1989
1989
Enhanced glomerular thromboxane A2 mediates some pathophysiologic effect of platelet-activating factor in rabbit nephrotoxic nephritis: evidence from biochemical measurements and inhibitor trials.
Previous studies have shown that platelet-activating factor (PAF) receptor blocking has a protective effect on rabbit nephrotoxic… 
Highly Cited
1988
Highly Cited
1988
Characterization of receptors for platelet‐activating factor on platelets, polymorphonuclear leukocytes and macrophages
1 We have compared the potency of the putative platelet‐activating factor (Paf) receptor antagonists (WEB 2086, L‐652,731 and BN… 
1988
1988
Inhibitory effect of platelet-activating factor (PAF) on luteinizing hormone-releasing hormone and somatostatin release from rat median eminence in vitro correlated with the characterization of…
Platelet-activating factor (PAF) exhibits a wide range of biological activities, including the stimulation of secretory processes… 
1988
1988
Gastric mucosal damage induced by local intra‐arterial administration of Paf in the rat
1 A technique for the close‐arterial administration of substances to the rat stomach in vivo has been developed. 2 Intra‐arterial… 
1987
1987
Platelet-activating factor (PAF) stimulates the PAF-synthesizing enzyme acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O2-acetyltransferase and PAF synthesis in neutrophils.
Platelet activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine; PAF) induced in isolated rat peritoneal and human… 
Highly Cited
1987
Highly Cited
1987
Platelet-activating factor mediates endotoxin-induced acute renal insufficiency in rats.
Platelet-activating factor (PAF) may contribute to the renal functional impairment of endotoxemia. We therefore examined 1) the… 
Highly Cited
1986
Highly Cited
1986
Release of platelet activating factor and its involvement in the first phase of carrageenin-induced rat foot edema.
Highly Cited
1985
Highly Cited
1985
trans-2,5-Bis-(3,4,5-trimethoxyphenyl)tetrahydrofuran. An orally active specific and competitive receptor antagonist of platelet activating factor.
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