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Kynurenic Acid

Known as: 2-Quinolinecarboxylic acid, 4-hydroxy-, Acid, Kynurenic, Kynurenic Acid [Chemical/Ingredient] 
A broad-spectrum excitatory amino acid antagonist used as a research tool.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
  • B. Pedersen
  • Nature Reviews Endocrinology
  • 2019
  • Corpus ID: 71143821
Neurological and mental illnesses account for a considerable proportion of the global burden of disease. Exercise has many… Expand
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Review
2018
Review
2018
HighlightsWe conducted the first meta‐analysis on metabolite levels of kynurenine pathway in patients with depression.Out of 899… Expand
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Review
2018
Review
2018
In this review, the potential causes of ageing are discussed. We seek to gain insight into the main physiological functions of… Expand
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Review
2018
Review
2018
The gut microbiota influences the health of the host, especially with regard to gut immune homeostasis and the intestinal immune… Expand
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Highly Cited
2006
Highly Cited
2006
Local catabolism of the essential amino acid tryptophan is considered an important mechanism in regulating immunological and… Expand
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Highly Cited
2001
Highly Cited
2001
The tryptophan metabolite kynurenic acid (KYNA) has long been recognized as an NMDA receptor antagonist. Here, interactions… Expand
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Highly Cited
2001
Highly Cited
2001
Kynurenic acid is an endogenous glutamate antagonist with a preferential action at the glycine-site of the N-methyl D-aspartate… Expand
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Highly Cited
2001
Highly Cited
2001
The tryptophan metabolite kynurenic acid (KYNA) has long been recognized as an NMDA receptor antagonist. Here, interactions… Expand
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Review
1993
Review
1993
  • T. Stone
  • Pharmacological reviews
  • 1993
  • Corpus ID: 37906763
In a little more than 10 years, the kynurenine metabolites of tryptophan have emerged from their former position as biochemical… Expand
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Highly Cited
1990
Highly Cited
1990
Abstract: Recent evidence suggests that there may be over‐activation of the N‐methyl‐D‐aspartate (NMDA) subtype of excitatory… Expand
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