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Identification of branching paraventricular neurons of the hypothalamus that project to the rostroventrolateral medulla and spinal cord
The paraventricular nucleus of the hypothalamus has efferent connections to autonomic nuclei known to ultimately regulate cardiovascular function. Studies have revealed projections to the sympathetic… Expand
Neurochemistry of the paraventricular nucleus of the hypothalamus: Implications for cardiovascular regulation
- S. Pyner
- Biology, Medicine
- Journal of Chemical Neuroanatomy
- 1 November 2009
The paraventricular nucleus of the hypothalamus (PVN) is an important site for autonomic and endocrine homeostasis. The PVN integrates specific afferent stimuli to produce an appropriate differential… Expand
CONTROL OF SYMPATHETIC OUTFLOWS BY THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS
- J. Coote, Z. Yang, S. Pyner, J. Deering
- Chemistry, Medicine
- Clinical and experimental pharmacology…
- 1 June 1998
1. The functional role of the paraventricular nucleus (PVN) has been examined by studying its connections with cardiovascular neurons in the medulla and spinal cord and its influence on activity in… Expand
The paraventricular nucleus of the hypothalamus sends efferents to the spinal cord of the rat that closely appose sympathetic preganglionic neurones projecting to the stellate ganglion
- R. Ranson, K. Motawei, S. Pyner, J. Coote
- Biology, Medicine
- Experimental Brain Research
- 1 May 1998
Abstract Using a combination of anterograde and retrograde neuronal tract-tracing techniques, the descending projections from the paraventricular nucleus of the hypothalamus (PVN) to the brain/spinal… Expand
Identification of an efferent projection from the paraventricular nucleus of the hypothalamus terminating close to spinally projecting rostral ventrolateral medullary neurons
The paraventricular nucleus of the hypothalamus is increasingly being viewed as an important site for cardiovascular integration because of its connections to regions in the brain and spinal cord… Expand
A comparison between the adult rat and neonate rat of the architecture of sympathetic preganglionic neurones projecting to the superior cervical ganglion, stellate ganglion and adrenal medulla.
Sympathetic preganglionic neurones (SPN) projecting to the superior cervical ganglion (SCG) and adrenal medulla (AM) in the neonate (< 14 days) and SCG, stellate ganglion (SG) and AM in the adult rat… Expand
Evidence that sympathetic preganglionic neurones are arranged in target‐specific columns in the thoracic spinal cord of the rat
It is recognised that selective activation of different target‐specific sympathetic preganglionic neurones forms the basis of many autonomic responses. The anatomical basis for this could be the… Expand
Right Atrial Stretch Induces Renal Nerve Inhibition and c‐fos Expression in Parvocellular Neurones of the Paraventricular Nucleus in Rats
- S. Pyner, J. Deering, J. Coote
- Medicine
- Experimental physiology
- 1 January 2002
The paraventricular nucleus of the hypothalamus plays a pivotol role in the regulation of plasma volume. Part of the response to an increase in volume load is an inhibition of renal sympathetic nerve… Expand
The projection and synaptic organisation of NTS afferent connections with presympathetic neurons, GABA and nNOS neurons in the paraventricular nucleus of the hypothalamus
- V.S. Affleck, J. Coote, S. Pyner
- Chemistry, Medicine
- Neuroscience
- 6 September 2012
Highlights ► Ascending NTS fibres target PVN-associated neurons. ► Suggest glutamate as the neurotransmitter. ► Anatomical basis for the different functions of cardiovascular receptors.
Terminals of paraventricular spinal neurones are closely associated with adrenal medullary sympathetic preganglionic neurones: immunocytochemical evidence for vasopressin as a possible…
- K. Motawei, S. Pyner, R. Ranson, Maher M. Kamel, J. Coote
- Chemistry, Medicine
- Experimental Brain Research
- 15 April 1999
Abstract A recent study using transsynaptically transported pseudorabies virus, injected into the adrenal gland, showed labelled neurones in the paraventricular nucleus (PVN) of the hypothalamus,… Expand
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