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Kinome

The set of all kinases expressed in a cell or contained in a genome.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Kinome Expansion in the Fusarium oxysporum Species Complex Driven by Accessory Chromosomes
Isolates of Fusarium oxysporum are adapted to survive a wide range of host and nonhost conditions. In addition, F. oxysporum was… 
Review
2017
Review
2017
Technological advances for interrogating the human kinome.
There is increasing appreciation among researchers and clinicians of the value of investigating biology and pathobiology at the… 
Review
2017
Review
2017
Recent advances in methods to assess the activity of the kinome
Protein and lipid kinases are deregulated in most, if not all, cancers and are among the most valuable therapeutic targets in… 
2016
2016
A High-Throughput Targeted Proteomic Approach for Comprehensive Profiling of Methylglyoxal-Induced Perturbations of the Human Kinome.
Kinases are one of the most important families of enzymes that are involved in numerous cell signaling processes. Existing… 
2015
2015
Characterization of the Host Response to Pichinde Virus Infection in the Syrian Golden Hamster by Species-Specific Kinome Analysis*
The Syrian golden hamster has been increasingly used to study viral hemorrhagic fever (VHF) pathogenesis and countermeasure… 
2015
2015
Induction of tissue- and stressor-specific kinomic responses in chickens exposed to hot and cold stresses.
Defining cellular responses at the level of global cellular kinase (kinome) activity is a powerful approach to deciphering… 
2011
2011
Interrogating the kinome
Comprehensive studies of the kinome set the stage for discovering the next generation of kinase-directed drugs. 
2010
2010
Analysis of Kinase Gene Expression Patterns across 5681 Human Tissue Samples Reveals Functional Genomic Taxonomy of the Kinome
Kinases play key roles in cell signaling and represent major targets for drug development, but the regulation of their activation… 
2005
2005
Probing the kinome
Researchers are eager to map out all the signaling pathways regulated by protein kinases. Many new protocols and reagents are… 
Review
2004
Review
2004
Kinase chemogenomics: targeting the human kinome for target validation and drug discovery.
Chemogenomics is a gene family-based approach to drug discovery and target validation. This review will summarize the application… 
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