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Kinome

The set of all kinases expressed in a cell or contained in a genome.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Among major problems in dealing with leukemic disease is the build-up of resistance against therapy
2016
2016
Moderated Poster session - Genetic, Epigenetic & Integrative
Introduction: Mitochondria are morphologically dynamic organelles which are constantly undergoing fusion and fission, processes… 
2015
2015
Screening for kinases regulating subcellular localization of clock proteins using human kinome library
국문 요약 ⅰ 차례 ⅳ 그림 차례 ⅶ 표 차례 ⅸ Ⅰ. 서론 1 A. 생체시계의 분자 생물학적 기전 1 B. 인산화에 의한 생체시계 조절 2 C. 핵 이동 5 D. 연구의 필요성 5… 
2014
2014
Breast Cancer + HER 2 shRNA Kinome Screen Identifies TBK 1 as a Therapeutic Target for
HER2þ breast cancer is currently treated with chemotherapy plus anti-HER2 inhibitors. Many patients do not respond or relapsewith… 
2014
2014
The Antiviral Potential of ERK / MAPK and PI 3 K / AKT / mTOR Signaling Modulation 1 for MERS-CoV Infection as Identified by Temporal Kinome Analysis 2 3 4 Running Title : Kinome analysis of MERS-CoV…
2011
2011
Selectivity and binding kinetics of mTOR inhibitors 1 Kinome-wide selectivity profiling of ATP-competitive mTOR ( mammalian target of rapamycin ) inhibitors and characterization of their binding…
Department of Cancer Biology, Dana Farber Cancer Institute, Department of Biological Chemistry and Molecular Pharmacology… 
2010
2010
A Kinome shRNA Screen to Identify Pathways That Regulate Megakaryocyte Polyploidization and New Targets for Differentiation Therapy
Abstract 89 Megakaryocytes undergo a unique mode of cell cycle called endomitosis, which is characterized by repeated rounds of… 
2009
2009
Vaccinia-related kinase ( VRK ) signaling in cell and tumor biology
VRK (vaccinia-related kinase) is a group of three proteins in the human kinome. These proteins, mainly VRK1 and VRK2, have been… 
2008
2008
[The kinome and glucocorticoid-induced apoptosis].
  • Ronit Vogt Sionov
  • Ai zheng = Aizheng = Chinese journal of cancer
  • 2008
  • Corpus ID: 1055066
In this perspective, I discuss the complex interplay between GC signaling and the kinome that ultimately determines the cell fate… 
2008
2008
A Strategy for Comprehensive Kinase Profiling for Drug Discovery
518 human protein kinase genes have been identified in the human kinome [1]. It is well known that protein kinases are key…