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Kinase Inhibitors [MoA]

Known as: Kinase Inhibitors 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The treatment of metastatic melanoma is still undergoing a process of major change. The two most important novel therapeutic… Expand
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Highly Cited
2017
Highly Cited
2017
BACKGROUND Ibrutinib, idelalisib, and venetoclax are approved for treating CLL patients in the US. However, there is no guidance… Expand
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2017
2017
Graphical abstract Figure. No Caption available. ABSTRACT Kinase inhibitors (KIs) are a rapidly expanding class of drugs used… Expand
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Review
2016
Review
2016
The survival of advanced metastatic melanoma has been greatly improved within the past few years. New therapeutic strategies like… Expand
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Highly Cited
2016
Highly Cited
2016
Novel agents such as the Bcl-2 inhibitor venetoclax (ABT-199) are changing treatment paradigms for chronic lymphocytic leukemia… Expand
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2016
2016
The FDA has approved 31 small-molecule kinase inhibitors (KIs) for human use as of November 2016, with six having black box… Expand
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Highly Cited
2015
Highly Cited
2015
Background: LRRK2 kinase activity has been implicated in Parkinson disease (PD). Results: LRRK2 kinase inhibition attenuated… Expand
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Highly Cited
2015
Highly Cited
2015
A major clinical problem in chronic lymphocytic leukemia (CLL) is development of chemoresistance, which can be caused by genetic… Expand
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Highly Cited
2015
Highly Cited
2015
Solid supported probes have proven to be an efficient tool for chemical proteomics. The kinobeads technology features kinase… Expand
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2015
2015
Pharmacological inhibition of phosphatiylinositide‐3‐kinase (PI3K)‐mediated signaling holds great promise for treating chronic… Expand
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